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miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression.
Escobar TM, Kanellopoulou C, Kugler DG, Kilaru G, Nguyen CK, Nagarajan V, Bhairavabhotla RK, Northrup D, Zahr R, Burr P, Liu X, Zhao K, Sher A, Jankovic D, Zhu J, Muljo SA. Escobar TM, et al. Immunity. 2014 Jun 19;40(6):865-79. doi: 10.1016/j.immuni.2014.03.014. Epub 2014 May 22. Immunity. 2014. PMID: 24856900 Free PMC article.
Transcriptome profiling of human FoxP3+ regulatory T cells.
Bhairavabhotla R, Kim YC, Glass DD, Escobar TM, Patel MC, Zahr R, Nguyen CK, Kilaru GK, Muljo SA, Shevach EM. Bhairavabhotla R, et al. Among authors: escobar tm. Hum Immunol. 2016 Feb;77(2):201-13. doi: 10.1016/j.humimm.2015.12.004. Epub 2015 Dec 10. Hum Immunol. 2016. PMID: 26686412 Free PMC article.
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate.
Ji Y, Fioravanti J, Zhu W, Wang H, Wu T, Hu J, Lacey NE, Gautam S, Le Gall JB, Yang X, Hocker JD, Escobar TM, He S, Dell'Orso S, Hawk NV, Kapoor V, Telford WG, Di Croce L, Muljo SA, Zhang Y, Sartorelli V, Gattinoni L. Ji Y, et al. Among authors: escobar tm. Nat Commun. 2019 May 14;10(1):2157. doi: 10.1038/s41467-019-09882-8. Nat Commun. 2019. PMID: 31089138 Free PMC article.
MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer.
Dudda JC, Salaun B, Ji Y, Palmer DC, Monnot GC, Merck E, Boudousquie C, Utzschneider DT, Escobar TM, Perret R, Muljo SA, Hebeisen M, Rufer N, Zehn D, Donda A, Restifo NP, Held W, Gattinoni L, Romero P. Dudda JC, et al. Among authors: escobar tm. Immunity. 2013 Apr 18;38(4):742-53. doi: 10.1016/j.immuni.2012.12.006. Immunity. 2013. PMID: 23601686 Free PMC article.
DNA methylation status predicts cell type-specific enhancer activity.
Wiench M, John S, Baek S, Johnson TA, Sung MH, Escobar T, Simmons CA, Pearce KH, Biddie SC, Sabo PJ, Thurman RE, Stamatoyannopoulos JA, Hager GL. Wiench M, et al. EMBO J. 2011 Jun 24;30(15):3028-39. doi: 10.1038/emboj.2011.210. EMBO J. 2011. PMID: 21701563 Free PMC article.
16 results