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[Study on chemical components of Hypericum himalaicum and mechanism of anti-inflammatory based on network pharmacology and molecular docking technology].
Zhou XT, Yang YC, Cheng HT, Pang KJ, Cheng M, Song P, Yang XZ, Yuan Y. Zhou XT, et al. Zhongguo Zhong Yao Za Zhi. 2024 Feb;49(4):951-960. doi: 10.19540/j.cnki.cjcmm.20231107.201. Zhongguo Zhong Yao Za Zhi. 2024. PMID: 38621902 Chinese.
The structure of the isolated compounds was identified by modern spectral techniques(NMR, MS, IR, and UV), and the potential anti-inflammatory targets and action pathways were analyzed and predicted by network pharmacology and molecular docking methods.Ten compounds were isolated …
The structure of the isolated compounds was identified by modern spectral techniques(NMR, MS, IR, and UV), and the potential anti-inflammato …
Developmental cervical spinal canal size: population reference range.
Griffith JF, Lee JCH. Griffith JF, et al. Quant Imaging Med Surg. 2024 Apr 3;14(4):3044-3059. doi: 10.21037/qims-22-1395. Epub 2024 Mar 22. Quant Imaging Med Surg. 2024. PMID: 38617159 Free PMC article.
Using a manually operated segmentation program, spinal canal, and vertebral body cross-sectional area (CSA), anteroposterior (AP) sagittal diameter, and width were measured at each level from C3-C7. Patient height and weight were measured. RESULTS: Considerable variation i …
Using a manually operated segmentation program, spinal canal, and vertebral body cross-sectional area (CSA), anteroposterior (AP) sagittal d …
Emerging Vanadium-Doped Cobalt Chloride Carbonate Hydroxide for Flexible Electrochromic Micro-Supercapacitor: Charged-State Prediction from RGB Input by ANN Model.
Pradhan L, Kamila S, Padhy G, Das DP, Jena BK. Pradhan L, et al. Small. 2024 Apr 11:e2401238. doi: 10.1002/smll.202401238. Online ahead of print. Small. 2024. PMID: 38602230
The V-C(3)H NSs material exhibits a high specific capacitance of 1219.9 F g(-1) at 1 mV s(-1) with a capacitance retention of 100% over 30 000 CV cycles. ...
The V-C(3)H NSs material exhibits a high specific capacitance of 1219.9 F g(-1) at 1 mV s(-1) with a capacitance retention of 100% ov …
Supergravity-Steered Generic Manufacturing of Nanosheets-Embedded Nanocomposite Hydrogel with Highly-Oriented, Heterogenous Architecture.
Xu GC, Nie Y, Li HN, Li WL, Lin WT, Xue YR, Li K, Fang Y, Liang HQ, Yang HC, Zhan H, Zhang C, Lü C, Xu ZK. Xu GC, et al. Adv Mater. 2024 Apr 10:e2400075. doi: 10.1002/adma.202400075. Online ahead of print. Adv Mater. 2024. PMID: 38597782
Such a synergetic effect allows to yield heterogenous nanocomposite hydrogels with a high-orientation MXene-rich layer (orientation degree, f = 0.83) and a polymer-rich layer. We further demonstrate that MXene-based nanocomposite hydrogels leverage their high-orientation, …
Such a synergetic effect allows to yield heterogenous nanocomposite hydrogels with a high-orientation MXene-rich layer (orientation degree, …
MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus.
Wang T, Song D, Li X, Luo Y, Yang D, Liu X, Kong X, Xing Y, Bi S, Zhang Y, Hu T, Zhang Y, Dai S, Shao Z, Chen D, Hou J, Ballestar E, Cai J, Zheng F, Yang JY. Wang T, et al. Cell Commun Signal. 2024 Apr 8;22(1):220. doi: 10.1186/s12964-024-01601-1. Cell Commun Signal. 2024. PMID: 38589923 Free PMC article.
In a transgenic mouse model, the induction of miR-574-5p overexpression is associated with increased secretion of antinuclear and anti-dsDNA antibodies, increased IgG and C3 deposit in the kidney, elevated expression of inflammatory genes in the spleen. ...
In a transgenic mouse model, the induction of miR-574-5p overexpression is associated with increased secretion of antinuclear and anti-dsDNA …
Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis.
Bowen JI, Zhong X, Gao K, Reed B, Crump MP, Wang L, Willis CL. Bowen JI, et al. Chem Sci. 2024 Mar 12;15(14):5319-5326. doi: 10.1039/d4sc00720d. eCollection 2024 Apr 3. Chem Sci. 2024. PMID: 38577359 Free PMC article.
Herein we report a flexible modular approach for the total synthesis of ambruticins which is used to prepare ambruticins F and S as well as in the first total synthesis of 20,21-dihydroambruticin F. ...An efficient electroporation method enabled gene knockout experi …
Herein we report a flexible modular approach for the total synthesis of ambruticins which is used to prepare ambruticins F and S as w …
Ergosterols with rare peroxide, oxetane ring moiety, and a lactone ring from Aspergillus spectabilis and their immunosuppressive activities.
Wei M, Liao H, Li Q, Deng X, Gao C, Ding N, Sun W, Zhu H, Guo J, Chen C, Zhang Y. Wei M, et al. Phytochemistry. 2024 Apr 2;222:114070. doi: 10.1016/j.phytochem.2024.114070. Online ahead of print. Phytochemistry. 2024. PMID: 38574957
Structurally, spectasteroid A was a unique example of aromatic ergostane-type steroid that featured a rare peroxide ring moiety; spectasteroid B contained a rare oxetane ring system formed between C-9 and C-14; and spectasteroid C was an unusual 3,4-seco-ergostane steroid with an …
Structurally, spectasteroid A was a unique example of aromatic ergostane-type steroid that featured a rare peroxide ring moiety; spectastero …
CSMD1 regulates brain complement activity and circuit development.
Baum ML, Wilton DK, Fox RG, Carey A, Hsu YH, Hu R, Jäntti HJ, Fahey JB, Muthukumar AK, Salla N, Crotty W, Scott-Hewitt N, Bien E, Sabatini DA, Lanser TB, Frouin A, Gergits F, Håvik B, Gialeli C, Nacu E, Lage K, Blom AM, Eggan K, McCarroll SA, Johnson MB, Stevens B. Baum ML, et al. Brain Behav Immun. 2024 Mar 27;119:317-332. doi: 10.1016/j.bbi.2024.03.041. Online ahead of print. Brain Behav Immun. 2024. PMID: 38552925 Free article.
Mice lacking Csmd1 displayed increased levels of complement component C3, an increased colocalization of C3 with presynaptic terminals, fewer retinogeniculate synapses, and aberrant segregation of eye-specific retinal inputs to the visual thalamus during the critica …
Mice lacking Csmd1 displayed increased levels of complement component C3, an increased colocalization of C3 with presynaptic t …
4,364 results