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TH17 cells express ST2 and are controlled by the alarmin IL-33 in the small intestine.
Pascual-Reguant A, Bayat Sarmadi J, Baumann C, Noster R, Cirera-Salinas D, Curato C, Pelczar P, Huber S, Zielinski CE, Löhning M, Hauser AE, Esplugues E. Pascual-Reguant A, et al. Among authors: esplugues e. Mucosal Immunol. 2017 Nov;10(6):1431-1442. doi: 10.1038/mi.2017.5. Epub 2017 Feb 15. Mucosal Immunol. 2017. PMID: 28198366 Free article.
Control of TH17 cells occurs in the small intestine.
Esplugues E, Huber S, Gagliani N, Hauser AE, Town T, Wan YY, O'Connor W Jr, Rongvaux A, Van Rooijen N, Haberman AM, Iwakura Y, Kuchroo VK, Kolls JK, Bluestone JA, Herold KC, Flavell RA. Esplugues E, et al. Nature. 2011 Jul 17;475(7357):514-8. doi: 10.1038/nature10228. Nature. 2011. PMID: 21765430 Free PMC article.
The role of TH17-associated cytokines in health and disease.
O'Connor W Jr, Esplugues E, Huber S. O'Connor W Jr, et al. Among authors: esplugues e. J Immunol Res. 2014;2014:936270. doi: 10.1155/2014/936270. Epub 2014 Apr 29. J Immunol Res. 2014. PMID: 24872959 Free PMC article. No abstract available.
IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo.
Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S. Brockmann L, et al. Among authors: esplugues e. J Immunol. 2017 Feb 1;198(3):1130-1141. doi: 10.4049/jimmunol.1601045. Epub 2016 Dec 21. J Immunol. 2017. PMID: 28003377 Free PMC article.
Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner.
Huber S, Gagliani N, Esplugues E, O'Connor W Jr, Huber FJ, Chaudhry A, Kamanaka M, Kobayashi Y, Booth CJ, Rudensky AY, Roncarolo MG, Battaglia M, Flavell RA. Huber S, et al. Among authors: esplugues e. Immunity. 2011 Apr 22;34(4):554-65. doi: 10.1016/j.immuni.2011.01.020. Immunity. 2011. PMID: 21511184 Free PMC article.
The induction and function of the anti-inflammatory fate of TH17 cells.
Xu H, Agalioti T, Zhao J, Steglich B, Wahib R, Vesely MCA, Bielecki P, Bailis W, Jackson R, Perez D, Izbicki J, Licona-Limón P, Kaartinen V, Geginat J, Esplugues E, Tolosa E, Huber S, Flavell RA, Gagliani N. Xu H, et al. Among authors: esplugues e. Nat Commun. 2020 Jul 3;11(1):3334. doi: 10.1038/s41467-020-17097-5. Nat Commun. 2020. PMID: 32620760 Free PMC article.
Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation.
Gagliani N, Amezcua Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limón P, Paiva RS, Ching T, Weaver C, Zi X, Pan X, Fan R, Garmire LX, Cotton MJ, Drier Y, Bernstein B, Geginat J, Stockinger B, Esplugues E, Huber S, Flavell RA. Gagliani N, et al. Among authors: esplugues e. Nature. 2015 Jul 9;523(7559):221-5. doi: 10.1038/nature14452. Epub 2015 Apr 29. Nature. 2015. PMID: 25924064 Free PMC article.
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.
Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M. Calcinotto A, et al. Among authors: esplugues e. Nat Commun. 2018 Dec 3;9(1):4832. doi: 10.1038/s41467-018-07305-8. Nat Commun. 2018. PMID: 30510245 Free PMC article.
36 results