Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency.
Cell Stem Cell. 2018 Aug 2;23(2):266-275.e6. doi: 10.1016/j.stem.2018.05.020. Epub 2018 Jun 14.
Cell Stem Cell. 2018.
PMID: 29910149
Free article.
It is still unclear how TFs actually orchestrate the opening of repressive chromatin during the long latency period of reprogramming. Here, we show that the orphan nuclear receptor Esrrb plays a pioneering role in recruiting the core pluripotency factors Oct4 …
It is still unclear how TFs actually orchestrate the opening of repressive chromatin during the long latency period of reprogramming. …