Esselens C - Search Results

1

Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway.

Esselens C, Oorschot V, Baert V, Raemaekers T, Spittaels K, Serneels L, Zheng H, Saftig P, De Strooper B, Klumperman J, Annaert W. Esselens C, et al. J Cell Biol. 2004 Sep 27;166(7):1041-54. doi: 10.1083/jcb.200406060. J Cell Biol. 2004. PMID: 15452145 Free PMC article.

2

Presenilin 1: more than just gamma-secretase.

Raemaekers T, Esselens C, Annaert W. Raemaekers T, et al. Among authors: esselens c. Biochem Soc Trans. 2005 Aug;33(Pt 4):559-62. doi: 10.1042/BST0330559. Biochem Soc Trans. 2005. PMID: 16042544 Review.

3

Peptides based on the presenilin-APP binding domain inhibit APP processing and Aβ production through interfering with the APP transmembrane domain.

Esselens C, Sannerud R, Gallardo R, Baert V, Kaden D, Serneels L, De Strooper B, Rousseau F, Multhaup G, Schymkowitz J, Langedijk JP, Annaert W. Esselens C, et al. FASEB J. 2012 Sep;26(9):3765-78. doi: 10.1096/fj.11-201368. Epub 2012 Jun 1. FASEB J. 2012. PMID: 22661005

4

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.

Sannerud R, Esselens C, Ejsmont P, Mattera R, Rochin L, Tharkeshwar AK, De Baets G, De Wever V, Habets R, Baert V, Vermeire W, Michiels C, Groot AJ, Wouters R, Dillen K, Vints K, Baatsen P, Munck S, Derua R, Waelkens E, Basi GS, Mercken M, Vooijs M, Bollen M, Schymkowitz J, Rousseau F, Bonifacino JS, Van Niel G, De Strooper B, Annaert W. Sannerud R, et al. Among authors: esselens c. Cell. 2016 Jun 30;166(1):193-208. doi: 10.1016/j.cell.2016.05.020. Epub 2016 Jun 9. Cell. 2016. PMID: 27293189 Free PMC article.

5

Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins.

Annaert WG, Esselens C, Baert V, Boeve C, Snellings G, Cupers P, Craessaerts K, De Strooper B. Annaert WG, et al. Among authors: esselens c. Neuron. 2001 Nov 20;32(4):579-89. doi: 10.1016/s0896-6273(01)00512-8. Neuron. 2001. PMID: 11719200 Free article.

6

Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability.

De Jonghe C, Esselens C, Kumar-Singh S, Craessaerts K, Serneels S, Checler F, Annaert W, Van Broeckhoven C, De Strooper B. De Jonghe C, et al. Among authors: esselens c. Hum Mol Genet. 2001 Aug 1;10(16):1665-71. doi: 10.1093/hmg/10.16.1665. Hum Mol Genet. 2001. PMID: 11487570

7

Proteomic identification of desmoglein 2 and activated leukocyte cell adhesion molecule as substrates of ADAM17 and ADAM10 by difference gel electrophoresis.

Bech-Serra JJ, Santiago-Josefat B, Esselens C, Saftig P, Baselga J, Arribas J, Canals F. Bech-Serra JJ, et al. Among authors: esselens c. Mol Cell Biol. 2006 Jul;26(13):5086-95. doi: 10.1128/MCB.02380-05. Mol Cell Biol. 2006. PMID: 16782893 Free PMC article.

8

ADAM17 (TACE) regulates TGFβ signaling through the cleavage of vasorin.

Malapeira J, Esselens C, Bech-Serra JJ, Canals F, Arribas J. Malapeira J, et al. Among authors: esselens c. Oncogene. 2011 Apr 21;30(16):1912-22. doi: 10.1038/onc.2010.565. Epub 2010 Dec 20. Oncogene. 2011. PMID: 21170088

9

Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17.

Esselens CW, Malapeira J, Colomé N, Moss M, Canals F, Arribas J. Esselens CW, et al. Biol Chem. 2008 Aug;389(8):1075-84. doi: 10.1515/bc.2008.121. Biol Chem. 2008. PMID: 18979631

10

Post-transcriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors.

Santiago-Josefat B, Esselens C, Bech-Serra JJ, Arribas J. Santiago-Josefat B, et al. Among authors: esselens c. J Biol Chem. 2007 Mar 16;282(11):8325-31. doi: 10.1074/jbc.M608826200. Epub 2007 Jan 16. J Biol Chem. 2007. PMID: 17227756 Free article.

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