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Essential role of the histone methyltransferase G9a in cocaine-induced plasticity.
Maze I, Covington HE 3rd, Dietz DM, LaPlant Q, Renthal W, Russo SJ, Mechanic M, Mouzon E, Neve RL, Haggarty SJ, Ren Y, Sampath SC, Hurd YL, Greengard P, Tarakhovsky A, Schaefer A, Nestler EJ. Maze I, et al. Science. 2010 Jan 8;327(5962):213-6. doi: 10.1126/science.1179438. Science. 2010. PMID: 20056891 Free PMC article.
In mice, we identified an essential role for histone 3 lysine 9 (H3K9) dimethylation and the lysine dimethyltransferase G9a in cocaine-induced structural and behavioral plasticity. ...This reduction in histone methylation wa …
In mice, we identified an essential role for histone 3 lysine 9 (H3K9) dimethylation and the lysine dimethyltransferase …
Targeting EHMT2/ G9a for cancer therapy: Progress and perspective.
Jan S, Dar MI, Wani R, Sandey J, Mushtaq I, Lateef S, Syed SH. Jan S, et al. Eur J Pharmacol. 2021 Feb 15;893:173827. doi: 10.1016/j.ejphar.2020.173827. Epub 2020 Dec 19. Eur J Pharmacol. 2021. PMID: 33347828
Euchromatic histone lysine methyltransferase-2, also known as G9a, is a ubiquitously expressed SET domain-containing histone lysine methyltransferase linked with both facultative and constitutive heterochromatin formation and transcriptional rep …
Euchromatic histone lysine methyltransferase-2, also known as G9a, is a ubiquitously expressed SET domain-containing …