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165 results
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Application of the EIIP/ISM bioinformatics concept in development of new drugs.
Veljkovic V, Veljkovic N, Esté JA, Hüther A, Dietrich U. Veljkovic V, et al. Among authors: este ja. Curr Med Chem. 2007;14(4):441-53. doi: 10.2174/092986707779941014. Curr Med Chem. 2007. PMID: 17305545 Review.
Polyanion inhibitors of human immunodeficiency virus and other viruses. Part 2. Polymerized anionic surfactants derived from amino acids and dipeptides.
Leydet A, El Hachemi H, Boyer B, Lamaty G, Roque JP, Schols D, Snoeck R, Andrei G, Ikeda S, Neyts J, Reymen D, Este J, Witvrouw M, De Clercq E. Leydet A, et al. J Med Chem. 1996 Apr 12;39(8):1626-34. doi: 10.1021/jm950358j. J Med Chem. 1996. PMID: 8648602
New targets and new drugs in the treatment of HIV.
López-Aldeguer J, Aguirrebengoa K, Arribas JR, Esté JA, Kindelán JM. López-Aldeguer J, et al. Among authors: este ja. Enferm Infecc Microbiol Clin. 2005 Jul;23 Suppl 2:25-40. Enferm Infecc Microbiol Clin. 2005. PMID: 16373002 Review. English, Spanish.
HIV-resistance to viral entry inhibitors.
Menéndez-Arias L, Esté JA. Menéndez-Arias L, et al. Among authors: este ja. Curr Pharm Des. 2004;10(15):1845-60. doi: 10.2174/1381612043384574. Curr Pharm Des. 2004. PMID: 15180544 Review.
New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors.
Famiglini V, La Regina G, Coluccia A, Pelliccia S, Brancale A, Maga G, Crespan E, Badia R, Clotet B, Esté JA, Cirilli R, Novellino E, Silvestri R. Famiglini V, et al. Among authors: este ja. Eur J Med Chem. 2014 Jun 10;80:101-11. doi: 10.1016/j.ejmech.2014.04.027. Epub 2014 Apr 12. Eur J Med Chem. 2014. PMID: 24769348
Virus entry as a target for anti-HIV intervention.
Esté JA. Esté JA. Curr Med Chem. 2003 Sep;10(17):1617-32. doi: 10.2174/0929867033457098. Curr Med Chem. 2003. PMID: 12871111 Review.
Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV-1 Agents.
Famiglini V, La Regina G, Coluccia A, Masci D, Brancale A, Badia R, Riveira-Muñoz E, Esté JA, Crespan E, Brambilla A, Maga G, Catalano M, Limatola C, Formica FR, Cirilli R, Novellino E, Silvestri R. Famiglini V, et al. Among authors: este ja. J Med Chem. 2017 Aug 10;60(15):6528-6547. doi: 10.1021/acs.jmedchem.6b01906. Epub 2017 Jul 5. J Med Chem. 2017. PMID: 28628334
Recent advances in combinatorial chemistry applied to development of anti-HIV drugs.
Pettersson S, Clotet-Codina I, Esté JA, Borrell JI, Teixidó J. Pettersson S, et al. Among authors: este ja. Mini Rev Med Chem. 2006 Jan;6(1):91-108. doi: 10.2174/138955706775197820. Mini Rev Med Chem. 2006. PMID: 16457634 Review.
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile.
Nawrozkij MB, Rotili D, Tarantino D, Botta G, Eremiychuk AS, Musmuca I, Ragno R, Samuele A, Zanoli S, Armand-Ugón M, Clotet-Codina I, Novakov IA, Orlinson BS, Maga G, Esté JA, Artico M, Mai A. Nawrozkij MB, et al. Among authors: este ja. J Med Chem. 2008 Aug 14;51(15):4641-52. doi: 10.1021/jm800340w. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630898
Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains.
Mai A, Artico M, Rotili D, Tarantino D, Clotet-Codina I, Armand-Ugón M, Ragno R, Simeoni S, Sbardella G, Nawrozkij MB, Samuele A, Maga G, Esté JA. Mai A, et al. Among authors: este ja. J Med Chem. 2007 Nov 1;50(22):5412-24. doi: 10.1021/jm070811e. Epub 2007 Oct 2. J Med Chem. 2007. PMID: 17910429
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