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A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect.
Lopez-Serra P, Marcilla M, Villanueva A, Ramos-Fernandez A, Palau A, Leal L, Wahi JE, Setien-Baranda F, Szczesna K, Moutinho C, Martinez-Cardus A, Heyn H, Sandoval J, Puertas S, Vidal A, Sanjuan X, Martinez-Balibrea E, Viñals F, Perales JC, Bramsem JB, Ørntoft TF, Andersen CL, Tabernero J, McDermott U, Boxer MB, Vander Heiden MG, Albar JP, Esteller M. Lopez-Serra P, et al. Among authors: esteller m. Nat Commun. 2014 Apr 3;5:3608. doi: 10.1038/ncomms4608. Nat Commun. 2014. PMID: 24699711 Free PMC article.
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. Fraga MF, et al. Among authors: esteller m. Nat Genet. 2005 Apr;37(4):391-400. doi: 10.1038/ng1531. Epub 2005 Mar 13. Nat Genet. 2005. PMID: 15765097
Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma.
Agrelo R, Setien F, Espada J, Artiga MJ, Rodriguez M, Pérez-Rosado A, Sanchez-Aguilera A, Fraga MF, Piris MA, Esteller M. Agrelo R, et al. Among authors: esteller m. J Clin Oncol. 2005 Jun 10;23(17):3940-7. doi: 10.1200/JCO.2005.11.650. Epub 2005 May 2. J Clin Oncol. 2005. PMID: 15867203
MGMT hypermethylation: a prognostic foe, a predictive friend.
Jacinto FV, Esteller M. Jacinto FV, et al. Among authors: esteller m. DNA Repair (Amst). 2007 Aug 1;6(8):1155-60. doi: 10.1016/j.dnarep.2007.03.013. Epub 2007 May 7. DNA Repair (Amst). 2007. PMID: 17482895 Review.
751 results