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636 results
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Targeting the histone orthography of cancer: drugs for writers, erasers and readers.
Simó-Riudalbas L, Esteller M. Simó-Riudalbas L, et al. Among authors: esteller m. Br J Pharmacol. 2015 Jun;172(11):2716-32. doi: 10.1111/bph.12844. Epub 2014 Sep 5. Br J Pharmacol. 2015. PMID: 25039449 Free PMC article. Review.
DNA demethylating agents and chromatin-remodelling drugs: which, how and why?
Villar-Garea A, Esteller M. Villar-Garea A, et al. Among authors: esteller m. Curr Drug Metab. 2003 Feb;4(1):11-31. doi: 10.2174/1389200033336757. Curr Drug Metab. 2003. PMID: 12570743 Review.
Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.
Villar-Garea A, Fraga MF, Espada J, Esteller M. Villar-Garea A, et al. Among authors: esteller m. Cancer Res. 2003 Aug 15;63(16):4984-9. Cancer Res. 2003. PMID: 12941824
Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern.
Espada J, Ballestar E, Fraga MF, Villar-Garea A, Juarranz A, Stockert JC, Robertson KD, Fuks F, Esteller M. Espada J, et al. Among authors: esteller m. J Biol Chem. 2004 Aug 27;279(35):37175-84. doi: 10.1074/jbc.M404842200. Epub 2004 Jun 25. J Biol Chem. 2004. PMID: 15220328
Histone deacetylase inhibitors: understanding a new wave of anticancer agents.
Villar-Garea A, Esteller M. Villar-Garea A, et al. Among authors: esteller m. Int J Cancer. 2004 Nov 1;112(2):171-8. doi: 10.1002/ijc.20372. Int J Cancer. 2004. PMID: 15352027 Review.
Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells.
Ropero S, Setien F, Espada J, Fraga MF, Herranz M, Asp J, Benassi MS, Franchi A, Patiño A, Ward LS, Bovee J, Cigudosa JC, Wim W, Esteller M. Ropero S, et al. Among authors: esteller m. Hum Mol Genet. 2004 Nov 15;13(22):2753-65. doi: 10.1093/hmg/ddh298. Epub 2004 Sep 22. Hum Mol Genet. 2004. PMID: 15385438
DNA methylation and cancer therapy: new developments and expectations.
Esteller M. Esteller M. Curr Opin Oncol. 2005 Jan;17(1):55-60. doi: 10.1097/01.cco.0000147383.04709.10. Curr Opin Oncol. 2005. PMID: 15608514 Review.
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Fraga MF, Ballestar E, Villar-Garea A, Boix-Chornet M, Espada J, Schotta G, Bonaldi T, Haydon C, Ropero S, Petrie K, Iyer NG, Pérez-Rosado A, Calvo E, Lopez JA, Cano A, Calasanz MJ, Colomer D, Piris MA, Ahn N, Imhof A, Caldas C, Jenuwein T, Esteller M. Fraga MF, et al. Among authors: esteller m. Nat Genet. 2005 Apr;37(4):391-400. doi: 10.1038/ng1531. Epub 2005 Mar 13. Nat Genet. 2005. PMID: 15765097
Aberrant DNA methylation as a cancer-inducing mechanism.
Esteller M. Esteller M. Annu Rev Pharmacol Toxicol. 2005;45:629-56. doi: 10.1146/annurev.pharmtox.45.120403.095832. Annu Rev Pharmacol Toxicol. 2005. PMID: 15822191 Review.
The epigenetic breakdown of cancer cells: from DNA methylation to histone modifications.
Ballestar E, Esteller M. Ballestar E, et al. Among authors: esteller m. Prog Mol Subcell Biol. 2005;38:169-81. doi: 10.1007/3-540-27310-7_7. Prog Mol Subcell Biol. 2005. PMID: 15881895 Review.
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