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N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells.
Nalla AK, Estes N, Patel J, Rao JS. Nalla AK, et al. Exp Cell Res. 2011 Oct 15;317(17):2512-21. doi: 10.1016/j.yexcr.2011.07.024. Epub 2011 Aug 9. Exp Cell Res. 2011. PMID: 21855541
Over the past decade, evidence continues to mount showing that N-cadherin is a critical protein in cancer progression and metastasis. ...Further, we noticed that blocking PI3K activity inhibited N-cadherin mediated MCP-1 expression. Our data demonstrated that N
Over the past decade, evidence continues to mount showing that N-cadherin is a critical protein in cancer progression and metastasis. …
Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer.
Asuthkar S, Stepanova V, Lebedeva T, Holterman AL, Estes N, Cines DB, Rao JS, Gondi CS. Asuthkar S, et al. Mol Biol Cell. 2013 Sep;24(17):2620-32. doi: 10.1091/mbc.E12-04-0306. Epub 2013 Jul 17. Mol Biol Cell. 2013. PMID: 23864708 Free PMC article.
Small interfering RNA-directed knockdown of uracil DNA glycosylase induces apoptosis and sensitizes human prostate cancer cells to genotoxic stress.
Pulukuri SM, Knost JA, Estes N, Rao JS. Pulukuri SM, et al. Mol Cancer Res. 2009 Aug;7(8):1285-93. doi: 10.1158/1541-7786.MCR-08-0508. Epub 2009 Aug 11. Mol Cancer Res. 2009. PMID: 19671688 Free PMC article.
Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kappa B activity leading to apoptosis in breast tumors.
Kunigal S, Lakka SS, Joseph P, Estes N, Rao JS. Kunigal S, et al. Clin Cancer Res. 2008 Jun 1;14(11):3617-26. doi: 10.1158/1078-0432.CCR-07-2060. Clin Cancer Res. 2008. PMID: 18519796 Free PMC article.
RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.
Kunigal S, Lakka SS, Gondi CS, Estes N, Rao JS. Kunigal S, et al. Int J Cancer. 2007 Nov 15;121(10):2307-16. doi: 10.1002/ijc.22962. Int J Cancer. 2007. PMID: 17657740 Free PMC article.
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo.
Pulukuri SM, Gondi CS, Lakka SS, Jutla A, Estes N, Gujrati M, Rao JS. Pulukuri SM, et al. J Biol Chem. 2005 Oct 28;280(43):36529-40. doi: 10.1074/jbc.M503111200. Epub 2005 Aug 26. J Biol Chem. 2005. PMID: 16127174 Free PMC article.
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