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Methylmercury promotes prostacyclin release from cultured human brain microvascular endothelial cells via induction of cyclooxygenase-2 through activation of the EGFR-p38 MAPK pathway by inhibiting protein tyrosine phosphatase 1B activity.
Yoshida E, Kurita M, Eto K, Kumagai Y, Kaji T. Yoshida E, et al. Among authors: Eto K. Toxicology. 2017 Dec 1;392:40-46. doi: 10.1016/j.tox.2017.09.013. Epub 2017 Sep 25. Toxicology. 2017. PMID: 28958600
Suppression of fibroblast growth factor-2 expression: possible mechanism underlying methylmercury-induced inhibition of the repair of wounded monolayers of cultured human brain microvascular endothelial cells.
Hirooka T, Fujiwara Y, Inoue S, Shinkai Y, Yamamoto C, Satoh M, Yasutake A, Eto K, Kaji T. Hirooka T, et al. Among authors: Eto K. J Toxicol Sci. 2009 Oct;34(4):433-9. doi: 10.2131/jts.34.433. J Toxicol Sci. 2009. PMID: 19652467
Increased methylmercury toxicity related to obesity in diabetic KK-Ay mice.
Yamamoto M, Yanagisawa R, Motomura E, Nakamura M, Sakamoto M, Takeya M, Eto K. Yamamoto M, et al. Among authors: Eto K. J Appl Toxicol. 2014 Aug;34(8):914-23. doi: 10.1002/jat.2954. Epub 2013 Nov 15. J Appl Toxicol. 2014. PMID: 24243536
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