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Discovery of New Aminosubstituted Pyrrolopyrimidines with Antiproliferative Activity Against Breast Cancer Cells and Investigation of their Effect Towards the PI3Kα Enzyme.
Daniilides K, Lougiakis N, Evangelidis T, Kostakis IK, Pouli N, Marakos P, Mikros E, Skaltsounis AL, Bach S, Baratte B, Ruchaud S, Karamani V, Papafotika A, Christoforidis S, Argyros O, Kouvari E, Tamvakopoulos C. Daniilides K, et al. Among authors: evangelidis t. Anticancer Agents Med Chem. 2017;17(7):990-1002. doi: 10.2174/1871520616666161207143450. Anticancer Agents Med Chem. 2017. PMID: 27928955
De novo design of a non-local β-sheet protein with high stability and accuracy.
Marcos E, Chidyausiku TM, McShan AC, Evangelidis T, Nerli S, Carter L, Nivón LG, Davis A, Oberdorfer G, Tripsianes K, Sgourakis NG, Baker D. Marcos E, et al. Among authors: evangelidis t. Nat Struct Mol Biol. 2018 Nov;25(11):1028-1034. doi: 10.1038/s41594-018-0141-6. Epub 2018 Oct 29. Nat Struct Mol Biol. 2018. PMID: 30374087 Free PMC article.