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Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2).
Oshima M, Dinchuk JE, Kargman SL, Oshima H, Hancock B, Kwong E, Trzaskos JM, Evans JF, Taketo MM. Oshima M, et al. Among authors: evans jf. Cell. 1996 Nov 29;87(5):803-9. doi: 10.1016/s0092-8674(00)81988-1. Cell. 1996. PMID: 8945508
Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice.
Yao M, Kargman S, Lam EC, Kelly CR, Zheng Y, Luk P, Kwong E, Evans JF, Wolfe MM. Yao M, et al. Among authors: evans jf. Cancer Res. 2003 Feb 1;63(3):586-92. Cancer Res. 2003. PMID: 12566300
Rofecoxib (Vioxx), a specific cyclooxygenase-2 inhibitor, is chemopreventive in a mouse model of colon cancer.
Evans JF. Evans JF. Am J Clin Oncol. 2003 Aug;26(4):S62-5. doi: 10.1097/01.COC.0000074159.05087.50. Am J Clin Oncol. 2003. PMID: 12902858
Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor.
Oshima M, Murai N, Kargman S, Arguello M, Luk P, Kwong E, Taketo MM, Evans JF. Oshima M, et al. Among authors: evans jf. Cancer Res. 2001 Feb 15;61(4):1733-40. Cancer Res. 2001. PMID: 11245490
Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor.
Lal G, Ash C, Hay K, Redston M, Kwong E, Hancock B, Mak T, Kargman S, Evans JF, Gallinger S. Lal G, et al. Among authors: evans jf. Cancer Res. 2001 Aug 15;61(16):6131-6. Cancer Res. 2001. PMID: 11507063
Cancer and cyclooxygenase-2 (COX-2) inhibition.
Evans JF, Kargman SL. Evans JF, et al. Curr Pharm Des. 2004;10(6):627-34. doi: 10.2174/1381612043453126. Curr Pharm Des. 2004. PMID: 14965325 Review.
Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2.
Brooks P, Emery P, Evans JF, Fenner H, Hawkey CJ, Patrono C, Smolen J, Breedveld F, Day R, Dougados M, Ehrich EW, Gijon-Baños J, Kvien TK, Van Rijswijk MH, Warner T, Zeidler H. Brooks P, et al. Among authors: evans jf. Rheumatology (Oxford). 1999 Aug;38(8):779-88. doi: 10.1093/rheumatology/38.8.779. Rheumatology (Oxford). 1999. PMID: 10501435
The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor.
Prasit P, Wang Z, Brideau C, Chan CC, Charleson S, Cromlish W, Ethier D, Evans JF, Ford-Hutchinson AW, Gauthier JY, Gordon R, Guay J, Gresser M, Kargman S, Kennedy B, Leblanc Y, Léger S, Mancini J, O'Neill GP, Ouellet M, Percival MD, Perrier H, Riendeau D, Rodger I, Zamboni R, et al. Prasit P, et al. Among authors: evans jf. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1773-8. doi: 10.1016/s0960-894x(99)00288-7. Bioorg Med Chem Lett. 1999. PMID: 10406640
mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline.
Obraztsova K, Basil MC, Rue R, Sivakumar A, Lin SM, Mukhitov AR, Gritsiuta AI, Evans JF, Kopp M, Katzen J, Robichaud A, Atochina-Vasserman EN, Li S, Carl J, Babu A, Morley MP, Cantu E, Beers MF, Frank DB, Morrisey EE, Krymskaya VP. Obraztsova K, et al. Among authors: evans jf. Nat Commun. 2020 Nov 6;11(1):5640. doi: 10.1038/s41467-020-18979-4. Nat Commun. 2020. PMID: 33159078 Free PMC article.
Inhibition of Growth of TSC2-Null Cells by a PI3K/mTOR Inhibitor but Not by a Selective MNK1/2 Inhibitor.
Evans JF, Rue RW, Mukhitov AR, Obraztsova K, Smith CJ, Krymskaya VP. Evans JF, et al. Biomolecules. 2019 Dec 24;10(1):28. doi: 10.3390/biom10010028. Biomolecules. 2019. PMID: 31878201 Free PMC article.
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