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Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses.
Everts B, Perona-Wright G, Smits HH, Hokke CH, van der Ham AJ, Fitzsimmons CM, Doenhoff MJ, van der Bosch J, Mohrs K, Haas H, Mohrs M, Yazdanbakhsh M, Schramm G. Everts B, et al. J Exp Med. 2009 Aug 3;206(8):1673-80. doi: 10.1084/jem.20082460. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635864 Free PMC article.
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.
Everts B, Hussaarts L, Driessen NN, Meevissen MH, Schramm G, van der Ham AJ, van der Hoeven B, Scholzen T, Burgdorf S, Mohrs M, Pearce EJ, Hokke CH, Haas H, Smits HH, Yazdanbakhsh M. Everts B, et al. J Exp Med. 2012 Sep 24;209(10):1753-67, S1. doi: 10.1084/jem.20111381. Epub 2012 Sep 10. J Exp Med. 2012. PMID: 22966004 Free PMC article.
FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.
Hansen IS, Krabbendam L, Bernink JH, Loayza-Puch F, Hoepel W, van Burgsteden JA, Kuijper EC, Buskens CJ, Bemelman WA, Zaat SAJ, Agami R, Vidarsson G, van den Brink GR, de Jong EC, Wildenberg ME, Baeten DLP, Everts B, den Dunnen J. Hansen IS, et al. Among authors: everts b. Nat Commun. 2018 Feb 28;9(1):863. doi: 10.1038/s41467-018-03318-5. Nat Commun. 2018. PMID: 29491406 Free PMC article.
Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.
Kaisar MMM, Ritter M, Del Fresno C, Jónasdóttir HS, van der Ham AJ, Pelgrom LR, Schramm G, Layland LE, Sancho D, Prazeres da Costa C, Giera M, Yazdanbakhsh M, Everts B. Kaisar MMM, et al. Among authors: everts b. PLoS Biol. 2018 Apr 18;16(4):e2005504. doi: 10.1371/journal.pbio.2005504. eCollection 2018 Apr. PLoS Biol. 2018. PMID: 29668708 Free PMC article.
90 results