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The following terms were not found in PubMed: HLA-B*5703, HLA-B*5703-Positive
Page 1
Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients.
Crawford H, Lumm W, Leslie A, Schaefer M, Boeras D, Prado JG, Tang J, Farmer P, Ndung'u T, Lakhi S, Gilmour J, Goepfert P, Walker BD, Kaslow R, Mulenga J, Allen S, Goulder PJ, Hunter E. Crawford H, et al. J Exp Med. 2009 Apr 13;206(4):909-21. doi: 10.1084/jem.20081984. Epub 2009 Mar 23. J Exp Med. 2009. PMID: 19307327 Free PMC article.
HLA-B*5703-restricted CTL responses select for escape mutations in three Gag p24 epitopes, in a predictable order. We show that the accumulation of these mutations sequentially reduces viral replicative capacity in vitro. ...Rapid disease progression is obser …
HLA-B*5703-restricted CTL responses select for escape mutations in three Gag p24 epitopes, in a predictable order. We show tha …
Demographic processes affect HIV-1 evolution in primary infection before the onset of selective processes.
Herbeck JT, Rolland M, Liu Y, McLaughlin S, McNevin J, Zhao H, Wong K, Stoddard JN, Raugi D, Sorensen S, Genowati I, Birditt B, McKay A, Diem K, Maust BS, Deng W, Collier AC, Stekler JD, McElrath MJ, Mullins JI. Herbeck JT, et al. J Virol. 2011 Aug;85(15):7523-34. doi: 10.1128/JVI.02697-10. Epub 2011 May 18. J Virol. 2011. PMID: 21593162 Free PMC article.
HIV-1 transmission and viral evolution in the first year of infection were studied in 11 individuals representing four transmitter-recipient pairs and three independent seroconverters. ...We showed that establishment of HIV-1 …
HIV-1 transmission and viral evolution in the first year of infection were studied in 11 individuals repr …
Modelling the evolution and spread of HIV immune escape mutants.
Fryer HR, Frater J, Duda A, Roberts MG; SPARTAC Trial Investigators; Phillips RE, McLean AR. Fryer HR, et al. PLoS Pathog. 2010 Nov 18;6(11):e1001196. doi: 10.1371/journal.ppat.1001196. PLoS Pathog. 2010. PMID: 21124991 Free PMC article.
Here we present a mathematical model of within-host evolution of escape mutants, transmission of these variants between hosts and subsequent reversion in new hosts. ...The several dozen CTL epitopes we survey from HIV-1 gag, RT and nef reveal a …
Here we present a mathematical model of within-host evolution of escape mutants, transmission of these variants between …
Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients.
Yue L, Pfafferott KJ, Baalwa J, Conrod K, Dong CC, Chui C, Rong R, Claiborne DT, Prince JL, Tang J, Ribeiro RM, Cormier E, Hahn BH, Perelson AS, Shaw GM, Karita E, Gilmour J, Goepfert P, Derdeyn CA, Allen SA, Borrow P, Hunter E. Yue L, et al. PLoS Pathog. 2015 Jan 8;11(1):e1004565. doi: 10.1371/journal.ppat.1004565. eCollection 2015 Jan. PLoS Pathog. 2015. PMID: 25569444 Free PMC article.
Control of virus replication in HIV-1 infection is critical to delaying disease progression. While cellular immune responses are a key determinant of control, relatively little is known about the contribution of the infecting virus to this process. To gain insight i …
Control of virus replication in HIV-1 infection is critical to delaying disease progression. While cellular immune responses a …
Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor.
Bailey JR, O'Connell K, Yang HC, Han Y, Xu J, Jilek B, Williams TM, Ray SC, Siliciano RF, Blankson JN. Bailey JR, et al. J Virol. 2008 Aug;82(15):7395-410. doi: 10.1128/JVI.00800-08. Epub 2008 May 21. J Virol. 2008. PMID: 18495769 Free PMC article.
In order to distinguish between these hypotheses, we studied differences in viral isolates and immune responses of an HIV-1 transmission pair. While both patients are HLA-B*57 positive, the transmitter progressed to AIDS, whereas the recipient, who is …
In order to distinguish between these hypotheses, we studied differences in viral isolates and immune responses of an HIV-1 …
Molecular evolution of human immunodeficiency virus type 1 upon transmission between human leukocyte antigen disparate donor-recipient pairs.
Navis M, Matas DE, Rachinger A, Koning FA, van Swieten P, Kootstra NA, Schuitemaker H. Navis M, et al. PLoS One. 2008 Jun 18;3(6):e2422. doi: 10.1371/journal.pone.0002422. PLoS One. 2008. PMID: 18560583 Free PMC article.
BACKGROUND: To address evolution of HIV-1 after transmission, we studied sequence dynamics in and outside predicted epitopes of cytotoxic T lymphocytes (CTL) in subtype B HIV-1 variants that were isolated from 5 therapy-naive horizontal H …
BACKGROUND: To address evolution of HIV-1 after transmission, we studied sequence dynamics in and outside predic …
Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences.
Eriksson EM, Liegler T, Keh CE, Karlsson AC, Holditch SJ, Pilcher CD, Loeb L, Nixon DF, Hecht FM. Eriksson EM, et al. PLoS One. 2015 Apr 28;10(4):e0120787. doi: 10.1371/journal.pone.0120787. eCollection 2014. PLoS One. 2015. PMID: 25919393 Free PMC article.
Although HIV-1 cytotoxic T cell (CTL) escape mutations are a common aspect during HIV-1 infection, less is known about the importance of T cell pressure in reversing HIV-1 virus back to a consensus sequences. In this study w …
Although HIV-1 cytotoxic T cell (CTL) escape mutations are a common aspect during HIV-1 infection, …