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81 results
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Metastasis inside-out: dissemination of cancer cell clusters with inverted polarity.
Ewald AJ. Ewald AJ. EMBO J. 2018 Apr 3;37(7):e99144. doi: 10.15252/embj.201899144. Epub 2018 Mar 9. EMBO J. 2018. PMID: 29523585 Free PMC article.
Cellular mechanisms regulating epithelial morphogenesis and cancer invasion.
Gray RS, Cheung KJ, Ewald AJ. Gray RS, et al. Among authors: ewald aj. Curr Opin Cell Biol. 2010 Oct;22(5):640-50. doi: 10.1016/j.ceb.2010.08.019. Epub 2010 Sep 9. Curr Opin Cell Biol. 2010. PMID: 20832275 Free PMC article. Review.
ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium.
Nguyen-Ngoc KV, Cheung KJ, Brenot A, Shamir ER, Gray RS, Hines WC, Yaswen P, Werb Z, Ewald AJ. Nguyen-Ngoc KV, et al. Among authors: ewald aj. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2595-604. doi: 10.1073/pnas.1212834109. Epub 2012 Aug 23. Proc Natl Acad Sci U S A. 2012. PMID: 22923691 Free PMC article.
The independent roles of mechanical, structural and adhesion characteristics of 3D hydrogels on the regulation of cancer invasion and dissemination.
Beck JN, Singh A, Rothenberg AR, Elisseeff JH, Ewald AJ. Beck JN, et al. Among authors: ewald aj. Biomaterials. 2013 Dec;34(37):9486-95. doi: 10.1016/j.biomaterials.2013.08.077. Epub 2013 Sep 14. Biomaterials. 2013. PMID: 24044993 Free PMC article.
Twist1-induced dissemination preserves epithelial identity and requires E-cadherin.
Shamir ER, Pappalardo E, Jorgens DM, Coutinho K, Tsai WT, Aziz K, Auer M, Tran PT, Bader JS, Ewald AJ. Shamir ER, et al. Among authors: ewald aj. J Cell Biol. 2014 Mar 3;204(5):839-56. doi: 10.1083/jcb.201306088. J Cell Biol. 2014. PMID: 24590176 Free PMC article.
Invasive leader cells: metastatic oncotarget.
Cheung KJ, Ewald AJ. Cheung KJ, et al. Among authors: ewald aj. Oncotarget. 2014 Mar 30;5(6):1390-1. doi: 10.18632/oncotarget.1870. Oncotarget. 2014. PMID: 24727787 Free PMC article. No abstract available.
Cancer: Sugar-coated cell signalling.
Ewald AJ, Egeblad M. Ewald AJ, et al. Nature. 2014 Jul 17;511(7509):298-9. doi: 10.1038/nature13506. Epub 2014 Jun 25. Nature. 2014. PMID: 25030162 No abstract available.
Illuminating breast cancer invasion: diverse roles for cell-cell interactions.
Cheung KJ, Ewald AJ. Cheung KJ, et al. Among authors: ewald aj. Curr Opin Cell Biol. 2014 Oct;30:99-111. doi: 10.1016/j.ceb.2014.07.003. Epub 2014 Aug 17. Curr Opin Cell Biol. 2014. PMID: 25137487 Free PMC article. Review.
Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters.
Cheung KJ, Padmanaban V, Silvestri V, Schipper K, Cohen JD, Fairchild AN, Gorin MA, Verdone JE, Pienta KJ, Bader JS, Ewald AJ. Cheung KJ, et al. Among authors: ewald aj. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E854-63. doi: 10.1073/pnas.1508541113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831077 Free PMC article.
A collective route to metastasis: Seeding by tumor cell clusters.
Cheung KJ, Ewald AJ. Cheung KJ, et al. Among authors: ewald aj. Science. 2016 Apr 8;352(6282):167-9. doi: 10.1126/science.aaf6546. Science. 2016. PMID: 27124449 Review.
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