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Year Number of Results
2002 2
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2010 6
2011 13
2012 12
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178 results

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Page 1
Florbetapir PET-assessed demyelination is associated with faster tau accumulation in an APOE ε4-dependent manner.
Rubinski A, Dewenter A, Zheng L, Franzmeier N, Stephenson H, Deming Y, Duering M, Gesierich B, Denecke J, Pham AV, Bendlin B, Ewers M; Alzheimer’s Disease Neuroimaging Initiative. Rubinski A, et al. Among authors: ewers m. Eur J Nucl Med Mol Imaging. 2023 Dec 5. doi: 10.1007/s00259-023-06530-8. Online ahead of print. Eur J Nucl Med Mol Imaging. 2023. PMID: 38049659
PURPOSE: The main objectives were to test whether (1) a decrease in myelin is associated with enhanced rate of fibrillar tau accumulation and cognitive decline in Alzheimer's disease, and (2) whether apolipoprotein E (APOE) epsilon4 genotype is associated with worse myelin …
PURPOSE: The main objectives were to test whether (1) a decrease in myelin is associated with enhanced rate of fibrillar tau accumulation an …
Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts.
Coenen M, Biessels GJ, DeCarli C, Fletcher EF, Maillard PM; Alzheimer's Disease Neuroimaging Initiative; Barkhof F, Barnes J, Benke T, Boomsma JMF, P L H Chen C, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Groeneveld O, Hilal S, Hofer E, Koek HL, Maier AB, McCreary CR, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Sudre CH, Steketee RME, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Wolters FJ, Xin X, Biesbroek JM, Kuijf HJ. Coenen M, et al. Among authors: ewers m. Neuroimage Clin. 2023 Nov 23;40:103547. doi: 10.1016/j.nicl.2023.103547. Online ahead of print. Neuroimage Clin. 2023. PMID: 38035457
WMH segmentations were provided by participating centers or performed in Utrecht and registered to the Montreal Neurological Institute (MNI)-152 brain template for spatial normalization. To determine WMH distribution frequencies, we calculated WMH probability maps at voxel …
WMH segmentations were provided by participating centers or performed in Utrecht and registered to the Montreal Neurological Institute …
ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels.
Steward A, Biel D, Dewenter A, Roemer S, Wagner F, Dehsarvi A, Rathore S, Otero Svaldi D, Higgins I, Brendel M, Dichgans M, Shcherbinin S, Ewers M, Franzmeier N. Steward A, et al. Among authors: ewers m. JAMA Neurol. 2023 Nov 6:e234038. doi: 10.1001/jamaneurol.2023.4038. Online ahead of print. JAMA Neurol. 2023. PMID: 37930695
DESIGN, SETTING, AND PARTICIPANTS: This cohort study including combined ApoE genotyping, amyloid PET, and longitudinal tau PET from 2 independent samples: the Alzheimer's Disease Neuroimaging Initiative (ADNI; n = 237; collected from April 2015 to August 2022) and Avid-A05 …
DESIGN, SETTING, AND PARTICIPANTS: This cohort study including combined ApoE genotyping, amyloid PET, and longitudinal tau PET from 2 indepe …
Fronto-striatal alterations correlate with apathy severity in behavioral variant frontotemporal dementia.
Upadhyay N, Spottke A, Schneider A, Hoffmann DC, Frommann I, Ballarini T, Fliessbach K, Bender B, Heekeren HR, Haynes JD, Ewers M, Düzel E, Glanz W, Dobisch L, Buerger K, Janowitz D, Levin J, Danek A, Teipel S, Kilimann I, Synofzik M, Wilke C, Peters O, Preis L, Priller J, Spruth EJ, Jessen F, Boecker H. Upadhyay N, et al. Among authors: ewers m. Brain Imaging Behav. 2023 Oct 19. doi: 10.1007/s11682-023-00812-3. Online ahead of print. Brain Imaging Behav. 2023. PMID: 37855956
Cognitive Trajectories in Preclinical and Prodromal Alzheimer's Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach.
Teipel SJ, Dyrba M, Levin F, Altenstein S, Berger M, Beyle A, Brosseron F, Buerger K, Burow L, Dobisch L, Ewers M, Fliessbach K, Frommann I, Glanz W, Goerss D, Gref D, Hansen N, Heneka MT, Incesoy EI, Janowitz D, Keles D, Kilimann I, Laske C, Lohse A, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rostamzadeh A, Roy N, Schmid M, Schneider A, Spottke A, Spruth EJ, Wiltfang J, Düzel E, Jessen F, Kleineidam L, Wagner M; DELCODE study group and the Alzheimer’s Disease Neuroimaging Initiative. Teipel SJ, et al. Among authors: ewers m. J Alzheimers Dis Rep. 2023 Sep 26;7(1):1055-1076. doi: 10.3233/ADR-230027. eCollection 2023. J Alzheimers Dis Rep. 2023. PMID: 37849637 Free PMC article.
BACKGROUND: Cognitive decline is a key outcome of clinical studies in Alzheimer's disease (AD). OBJECTIVE: To determine effects of global amyloid load as well as hippocampus and basal forebrain volumes on longitudinal rates and practice effects from repeated testing of dom …
BACKGROUND: Cognitive decline is a key outcome of clinical studies in Alzheimer's disease (AD). OBJECTIVE: To determine effects of gl …
Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease.
Zheng L, Rubinski A, Denecke J, Luan Y, Smith R, Strandberg O, Stomrud E, Ossenkoppele R, Svaldi DO, Higgins IA, Shcherbinin S, Pontecorvo MJ, Hansson O, Franzmeier N, Ewers M; Alzheimer's Disease Neuroimaging Initiative. Zheng L, et al. Among authors: ewers m. Ann Neurol. 2023 Oct 14. doi: 10.1002/ana.26818. Online ahead of print. Ann Neurol. 2023. PMID: 37837382
METHODS: We included 685 participants (395 amyloid-positive participants within AD spectrum and 290 amyloid-negative controls) with tau-PET and amyloid-PET from 3 studies (Alzheimer's Disease Neuroimaging Initiative, (18) F-AV-1451-A05, and BioFINDER-1). ...
METHODS: We included 685 participants (395 amyloid-positive participants within AD spectrum and 290 amyloid-negative controls) with tau-PET …
Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline.
Stark M, Wolfsgruber S, Kleineidam L, Frommann I, Altenstein S, Bartels C, Brosseron F, Buerger K, Burow L, Butryn M, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Hansen N, Heneka MT, Hinderer P, Incesoy EI, Janowitz D, Kilimann I, Kimmich O, Laske C, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Sanzenbacher C, Schneider A, Schott BH, Spottke A, Spruth EJ, Teipel S, Vogt IR, Wiltfang J, Duzel E, Jessen F, Wagner M. Stark M, et al. Among authors: ewers m. Neurology. 2023 Nov 21;101(21):e2185-e2196. doi: 10.1212/WNL.0000000000207844. Epub 2023 Oct 11. Neurology. 2023. PMID: 37821235 Free PMC article.
We defined MNPD as a performance of at least 0.5SD below the mean on a demographically adjusted total score derived from the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological assessment battery. We compared SCD patients with MNPD and those witho …
We defined MNPD as a performance of at least 0.5SD below the mean on a demographically adjusted total score derived from the Consortium to E …
Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression.
Waschkies KF, Soch J, Darna M, Richter A, Altenstein S, Beyle A, Brosseron F, Buchholz F, Butryn M, Dobisch L, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Janowitz D, Kilimann I, Lohse A, Munk MH, Rauchmann BS, Rostamzadeh A, Roy N, Spruth EJ, Dechent P, Heneka MT, Hetzer S, Ramirez A, Scheffler K, Buerger K, Laske C, Perneczky R, Peters O, Priller J, Schneider A, Spottke A, Teipel S, Düzel E, Jessen F, Wiltfang J, Schott BH, Kizilirmak JM. Waschkies KF, et al. Among authors: ewers m. Int J Geriatr Psychiatry. 2023 Oct;38(10):e6007. doi: 10.1002/gps.6007. Int J Geriatr Psychiatry. 2023. PMID: 37800601
BACKGROUND: Alzheimer's disease (AD) is often preceded by stages of cognitive impairment, namely subjective cognitive decline (SCD) and mild cognitive impairment (MCI). ...
BACKGROUND: Alzheimer's disease (AD) is often preceded by stages of cognitive impairment, namely subjective cognitive decline (SCD) a …
Long-term environmental enrichment is associated with better fornix microstructure in older adults.
Klimecki OM, Liebscher M, Gaubert M, Hayek D, Zarucha A, Dyrba M, Bartels C, Buerger K, Butryn M, Dechent P, Dobisch L, Ewers M, Fliessbach K, Freiesleben SD, Glanz W, Hetzer S, Janowitz D, Kilimann I, Kleineidam L, Laske C, Maier F, Munk MH, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Scheffler K, Schneider A, Spruth EJ, Spottke A, Teipel SJ, Wiltfang J, Wolfsgruber S, Yakupov R, Düzel E, Jessen F, Wagner M, Roeske S, Wirth M; DELCODE study group. Klimecki OM, et al. Among authors: ewers m. Front Aging Neurosci. 2023 Aug 28;15:1170879. doi: 10.3389/fnagi.2023.1170879. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37711996 Free PMC article.
BACKGROUND: Sustained environmental enrichment (EE) through a variety of leisure activities may decrease the risk of developing Alzheimer's disease. This cross-sectional cohort study investigated the association between long-term EE in young adulthood through middle life a …
BACKGROUND: Sustained environmental enrichment (EE) through a variety of leisure activities may decrease the risk of developing Alzheimer' …
Cortical Amyloid Burden Relates to Basal Forebrain Volume in Subjective Cognitive Decline.
Daamen M, Scheef L, Li S, Grothe MJ, Gaertner FC, Buchert R, Buerger K, Dobisch L, Drzezga A, Essler M, Ewers M, Fliessbach K, Herrera Melendez AL, Hetzer S, Janowitz D, Kilimann I, Krause BJ, Lange C, Laske C, Munk MH, Peters O, Priller J, Ramirez A, Reimold M, Rominger A, Rostamzadeh A, Roeske S, Roy N, Scheffler K, Schneider A, Spottke A, Spruth EJ, Teipel SJ, Wagner M, Düzel E, Jessen F, Boecker H; DELCODE Study Group. Daamen M, et al. Among authors: ewers m. J Alzheimers Dis. 2023;95(3):1013-1028. doi: 10.3233/JAD-230141. J Alzheimers Dis. 2023. PMID: 37638433
BACKGROUND: Atrophy of cholinergic basal forebrain (BF) nuclei is a frequent finding in magnetic resonance imaging (MRI) volumetry studies that examined patients with prodromal or clinical Alzheimer's disease (AD), but less clear for individuals in earlier stages of the cl …
BACKGROUND: Atrophy of cholinergic basal forebrain (BF) nuclei is a frequent finding in magnetic resonance imaging (MRI) volumetry studies t …
178 results