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Exostosin 1/exostosin 2-associated membranous nephropathy in undifferentiated connective tissue disease: a case report and literature review.
Ye H, Jiang X, Wu B, Xie X, Zheng Z. Ye H, et al. BMC Nephrol. 2025 Nov 25;26(1):665. doi: 10.1186/s12882-025-04596-0. BMC Nephrol. 2025. PMID: 41291566 Free PMC article.
While exostosin 1/exostosin 2 (EXT 1/EXT 2)-associated MN has been increasingly recognized in systemic autoimmune diseases such as lupus and Sjogren's syndrome, its association with UCTD has not been previously reported. CASE PRESENTATION: We pr …
While exostosin 1/exostosin 2 (EXT 1/EXT 2)-associated MN has been increasingly recognized in systemic au …
A Diagnostic and Therapeutic Dilemma Concerning Exostosin 1/Exostosin 2-associated Lupus-like Membranous Nephropathy with Positive Antinuclear Antibody in an Elderly Man with Various Immune Abnormalities.
Kawagoe M, Odajima K, Asakawa S, Nagura M, Arai S, Yamazaki O, Tamura Y, Ohashi R, Iwakura T, Yasuda H, Shibata S, Fujigaki Y. Kawagoe M, et al. Intern Med. 2023 Nov 1;62(21):3187-3194. doi: 10.2169/internalmedicine.1251-22. Epub 2023 Mar 22. Intern Med. 2023. PMID: 36948625 Free PMC article.
Exostosin 1 (EXT1) and exostosin 2 (EXT2)-associated membranous nephropathy (MN) may be associated with active autoimmune disease. ...
Exostosin 1 (EXT1) and exostosin 2 (EXT2)-associated membranous nephropathy (MN) may be associated with a …
Exostosin 1/Exostosin 2-Associated Membranous Nephropathy.
Sethi S, Madden BJ, Debiec H, Charlesworth MC, Gross L, Ravindran A, Hummel AM, Specks U, Fervenza FC, Ronco P. Sethi S, et al. J Am Soc Nephrol. 2019 Jun;30(6):1123-1136. doi: 10.1681/ASN.2018080852. Epub 2019 May 6. J Am Soc Nephrol. 2019. PMID: 31061139 Free PMC article.
BACKGROUND: In membranous nephropathy (MN), which is characterized by deposition of immune complexes along the glomerular basement membrane (GBM), phospholipase A2 receptor (PLA2R) and thrombospondin type 1 domain-containing 7A are target antigens in approximately 7 …
BACKGROUND: In membranous nephropathy (MN), which is characterized by deposition of immune complexes along the glomerular base …
Prevalence of neural epidermal growth factor-like 1- and exostosin 1/exostosin 2-associated membranous nephropathy: a single-center retrospective study in Japan.
Iwakura T, Ema C, Isobe S, Fujikura T, Ohashi N, Kato A, Yasuda H. Iwakura T, et al. Sci Rep. 2022 Feb 22;12(1):2967. doi: 10.1038/s41598-022-07037-2. Sci Rep. 2022. PMID: 35194125 Free PMC article.
Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. We previously reported that the prevalence of phospholipase A2 receptor (PLA2R)- and thrombospondin type 1 domain containing 7A (THSD7A)-associated MN patients in Japan is 52.7% and 9. …
Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. We previously reported that the prevalence o …