Extraction of polysaccharide from Ganoderma lucidum and its immune enhancement activity.
Int J Biol Macromol. 2010.
PMID: 20371373
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Extraction of polysaccharide from Ganoderma lucidum and its immune enhancement activity.
Int J Biol Macromol. 2010 Oct 1;47(3):336-41. doi: 10.1016/j.ijbiomac.2010.03.019. Epub 2010 Apr 4.
Int J Biol Macromol. 2010.
PMID: 20371373
In the present study, in order to maximize the yield of polysaccharides from Ganoderma lucidum, response surface methodology was employed to optimize the ultrasonic/microwave-assisted extraction (UMAE) conditions. ...The immunological assays results de …
In the present study, in order to maximize the yield of polysaccharides from Ganoderma lucidum, response surface method …
Optimization extraction of Ganoderma lucidum polysaccharides and its immunity and antioxidant activities.
Int J Biol Macromol. 2013 Apr;55:301-6. doi: 10.1016/j.ijbiomac.2013.01.022. Epub 2013 Jan 29.
Int J Biol Macromol. 2013.
PMID: 23370161
Extraction of Ganoderma lucidum polysaccharides (GLP) was optimized by response surface method (RSM). ...These findings show that GLP can enhance immunity and antioxidant activities in gastric cancer rats....
Extraction of Ganoderma lucidum polysaccharides (GLP) was optimized by response surface method (RSM). ...These f …
Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients.
Immunol Invest. 2003 Aug;32(3):201-15. doi: 10.1081/imm-120022979.
Immunol Invest. 2003.
PMID: 12916709
Clinical Trial.
Preclinical studies have established that the Ganoderma lucidum polysaccharide (GLPS) fractions have potent anti-tumor activity, which has been associated with the immuno-stimulating effects of GLPS. ...This study aimed to investigate the effects of Ga …
Preclinical studies have established that the Ganoderma lucidum polysaccharide (GLPS) fractions have potent anti-tumor …
An integrated microbiome and metabolomic analysis identifies immunoenhancing features of Ganoderma lucidum spores oil in mice.
Pharmacol Res. 2020 Aug;158:104937. doi: 10.1016/j.phrs.2020.104937. Epub 2020 May 26.
Pharmacol Res. 2020.
PMID: 32464331
Ganoderma lucidum (Leyss. ex Fr.) Karst. is a valuable dietary supplement used worldwide for promoting health as well as a medicinal fungus for handling fatigue, immunological disorders, and cancer. Previous studies have revealed the immunoenhancing effect of G. …
Ganoderma lucidum (Leyss. ex Fr.) Karst. is a valuable dietary supplement used worldwide for promoting health as well as a med …
Preferential induction of Th17 cells in vitro and in vivo by Fucogalactan from Ganoderma lucidum (Reishi).
Biochem Biophys Res Commun. 2012 May 25;422(1):174-80. doi: 10.1016/j.bbrc.2012.04.135. Epub 2012 May 1.
Biochem Biophys Res Commun. 2012.
PMID: 22569041
The mushroom known as Reishi (Ganoderma lucidum) has been used as an herbal medicine for tumor treatment and immune system activation. ...Reishi extracts as well as purified beta-glucan (Curdran) activated DCs and caused the …
The mushroom known as Reishi (Ganoderma lucidum) has been used as an herbal medicine for tumor treatment and immune …
Immunological activity of ginseng is enhanced by solid-state culture with Ganoderma lucidum mycelium.
J Med Food. 2014 Jan;17(1):150-60. doi: 10.1089/jmf.2013.3063.
J Med Food. 2014.
PMID: 24456366
Fresh ginseng was fermented with Ganoderma lucidum mycelium (GL) in solid-state culture to enhance its immunomodulatory activity. ...NaIO4 oxidation of FG-GL-CP-III significantly decreased its activity (64.0-79.2%). These results suggest that so …
Fresh ginseng was fermented with Ganoderma lucidum mycelium (GL) in solid-state culture to enhance its immunomodulatory …
Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest.
Life Sci. 2003 Apr 11;72(21):2381-90. doi: 10.1016/s0024-3205(03)00124-3.
Life Sci. 2003.
PMID: 12639703
Except for the immune enhancing properties of its polysaccharide constituent, very little is known about the anticancer activity of another major constituent, triterpenes. In this report, we studied the anticancer mechanism of triterpene-enriched ex …
Except for the immune enhancing properties of its polysaccharide constituent, very little is known about the anticancer …
Suppression of proliferation and oxidative stress by extracts of Ganoderma lucidum in the ovarian cancer cell line OVCAR-3.
Int J Mol Med. 2011 Dec;28(6):1065-9. doi: 10.3892/ijmm.2011.788. Epub 2011 Sep 1.
Int J Mol Med. 2011.
PMID: 21887458
Laboratory studies have shown that Ganoderma lucidum enhances immune functions and also inhibits growth of various cancer cells both in vitro and in vivo. However, the mechanism by which Ganoderma lucidum exerts its chemopreventive act …
Laboratory studies have shown that Ganoderma lucidum enhances immune functions and also inhibits growth of vario …
Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression.
J Cell Physiol. 2007 Aug;212(2):537-50. doi: 10.1002/jcp.21050.
J Cell Physiol. 2007.
PMID: 17474083
Free article.
We have previously reported that a well-characterized glycoprotein fraction containing fucose residues in an extract of Ganoderma lucidum polysaccharides (EORP) exerts certain immuno-modulation activity by stimulating the expression of inflammat …
We have previously reported that a well-characterized glycoprotein fraction containing fucose residues in an extract of Ganoderma …
Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3.
Oncol Lett. 2011 May;2(3):565-570. doi: 10.3892/ol.2011.275. Epub 2011 Mar 21.
Oncol Lett. 2011.
PMID: 22866120
Free PMC article.
The medicinal mushroom Ganoderma lucidum (G. lucidum) has been used for the treatment of various diseases, and is known for the immune-enhancing activity of its polysaccharide. ...This study investigated the anticancer mechanism of …
The medicinal mushroom Ganoderma lucidum (G. lucidum) has been used for the treatment of various diseases, and is known …