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Mitochondrial DNA stress primes the antiviral innate immune response.
West AP, Khoury-Hanold W, Staron M, Tal MC, Pineda CM, Lang SM, Bestwick M, Duguay BA, Raimundo N, MacDuff DA, Kaech SM, Smiley JR, Means RE, Iwasaki A, Shadel GS. West AP, et al. Nature. 2015 Apr 23;520(7548):553-7. doi: 10.1038/nature14156. Epub 2015 Feb 2. Nature. 2015. PMID: 25642965 Free PMC article.
Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease.
Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A. Pillai PS, et al. Science. 2016 Apr 22;352(6284):463-6. doi: 10.1126/science.aaf3926. Science. 2016. PMID: 27102485 Free PMC article.