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Year | Number of Results |
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2008 | 1 |
2010 | 1 |
2013 | 1 |
2024 | 0 |
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Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers.
Br J Clin Pharmacol. 2013 Feb;75(2):450-62. doi: 10.1111/j.1365-2125.2012.04364.x.
Br J Clin Pharmacol. 2013.
PMID: 22725836
Free PMC article.
Clinical Trial.
Role for protein kinase C delta in the functional activity of human UGT1A6: implications for drug-drug interactions between PKC inhibitors and UGT1A6.
Volak LP, Court MH.
Volak LP, et al.
Xenobiotica. 2010 May;40(5):306-18. doi: 10.3109/00498251003596817.
Xenobiotica. 2010.
PMID: 20196639
Free PMC article.
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Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor.
Volak LP, Ghirmai S, Cashman JR, Court MH.
Volak LP, et al.
Drug Metab Dispos. 2008 Aug;36(8):1594-605. doi: 10.1124/dmd.108.020552. Epub 2008 May 14.
Drug Metab Dispos. 2008.
PMID: 18480186
Free PMC article.
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