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Year Number of Results
2015 1
2016 2
2017 3
2018 2
2019 1
2020 0
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8 results
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Page 1
High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.
O'Meara TR, Duah K, Guo CX, Maxson ME, Gaudet RG, Koselny K, Wellington M, Powers ME, MacAlpine J, O'Meara MJ, Veri AO, Grinstein S, Noble SM, Krysan D, Gray-Owen SD, Cowen LE. O'Meara TR, et al. mBio. 2018 Aug 21;9(4):e01581-18. doi: 10.1128/mBio.01581-18. mBio. 2018. PMID: 30131363 Free PMC article.
Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen.
O'Meara TR, O'Meara MJ, Polvi EJ, Pourhaghighi MR, Liston SD, Lin ZY, Veri AO, Emili A, Gingras AC, Cowen LE. O'Meara TR, et al. PLoS Biol. 2019 Jul 8;17(7):e3000358. doi: 10.1371/journal.pbio.3000358. eCollection 2019 Jul. PLoS Biol. 2019. PMID: 31283755 Free PMC article.
The Hsp90 Chaperone Network Modulates Candida Virulence Traits.
O'Meara TR, Robbins N, Cowen LE. O'Meara TR, et al. Trends Microbiol. 2017 Oct;25(10):809-819. doi: 10.1016/j.tim.2017.05.003. Epub 2017 May 23. Trends Microbiol. 2017. PMID: 28549824 Free PMC article. Review.
Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress.
O'Meara TR, Veri AO, Polvi EJ, Li X, Valaei SF, Diezmann S, Cowen LE. O'Meara TR, et al. PLoS Genet. 2016 Jun 24;12(6):e1006142. doi: 10.1371/journal.pgen.1006142. eCollection 2016 Jun. PLoS Genet. 2016. PMID: 27341673 Free PMC article.
Global analysis of fungal morphology exposes mechanisms of host cell escape.
O'Meara TR, Veri AO, Ketela T, Jiang B, Roemer T, Cowen LE. O'Meara TR, et al. Nat Commun. 2015 Mar 31;6:6741. doi: 10.1038/ncomms7741. Nat Commun. 2015. PMID: 25824284 Free PMC article.
Extensive functional redundancy in the regulation of Candida albicans drug resistance and morphogenesis by lysine deacetylases Hos2, Hda1, Rpd3 and Rpd31.
Li X, Robbins N, O'Meara TR, Cowen LE. Li X, et al. Mol Microbiol. 2017 Feb;103(4):635-656. doi: 10.1111/mmi.13578. Epub 2016 Dec 14. Mol Microbiol. 2017. PMID: 27868254 Free PMC article.
Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A.
Xie JL, O'Meara TR, Polvi EJ, Robbins N, Cowen LE. Xie JL, et al. mSphere. 2017 Mar 1;2(2):e00056-17. doi: 10.1128/mSphere.00056-17. eCollection 2017 Mar-Apr. mSphere. 2017. PMID: 28261668 Free PMC article.