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FAM117B promotes gastric cancer growth and drug resistance by targeting the KEAP1/NRF2 signaling pathway.
Zhou Y, Chen Y, Shi Y, Wu L, Tan Y, Li T, Chen Y, Xia J, Hu R. Zhou Y, et al. J Clin Invest. 2023 Feb 1;133(3):e158705. doi: 10.1172/JCI158705. J Clin Invest. 2023. PMID: 36719368 Free PMC article.
Moreover, FAM117B-induced growth and chemoresistance of gastric cancer cells were NRF2 dependent. ...Collectively, our findings reveal that FAM117B is involved in promoting gastric cancer growth and drug resistance, and it could be exploited as a ca …
Moreover, FAM117B-induced growth and chemoresistance of gastric cancer cells were NRF2 dependent. ...Collectively, our finding …