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FGF-dependent metabolic control of vascular development.
Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M. Yu P, et al. Nature. 2017 May 11;545(7653):224-228. doi: 10.1038/nature22322. Epub 2017 May 3. Nature. 2017. PMID: 28467822 Free PMC article.
Recent studies have suggested that changes in cellular metabolism are important to these processes. Although much is known about vascular endothelial growth factor (VEGF)-dependent regulation of vascular development and metabolism, …
Recent studies have suggested that changes in cellular metabolism are important to these processes. Although much is known about v
Dgcr8 controls neural crest cells survival in cardiovascular development.
Chapnik E, Sasson V, Blelloch R, Hornstein E. Chapnik E, et al. Dev Biol. 2012 Feb 1;362(1):50-6. doi: 10.1016/j.ydbio.2011.11.008. Epub 2011 Nov 23. Dev Biol. 2012. PMID: 22138056 Free article.
To address the potential contribution of Dgcr8 insufficiency to cardiovascular development, we have inactivated Dgcr8 in cardiac neural crest cells (cNCCs). ...Our data uncover a new role of Dgcr8 in cardiovascular morphogenesis, plausibly as part of transmission mechanism …
To address the potential contribution of Dgcr8 insufficiency to cardiovascular development, we have inactivated Dgcr8 in cardiac neur …