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FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP.
Tsuchiya Y, Nakabayashi O, Nakano H. Tsuchiya Y, et al. Int J Mol Sci. 2015 Dec 18;16(12):30321-41. doi: 10.3390/ijms161226232. Int J Mol Sci. 2015. PMID: 26694384 Free PMC article. Review.
In addition, cFLIP regulates the formation of the death receptor-independent apoptotic platform named the ripoptosome. ...In this review, we summarize the current scientific findings from biochemical analyses, cell biological studies, mathematical modeling, and gene …
In addition, cFLIP regulates the formation of the death receptor-independent apoptotic platform named the ripoptosome. ...In t …
Roles of c-FLIP in Apoptosis, Necroptosis, and Autophagy.
Safa AR. Safa AR. J Carcinog Mutagen. 2013;Suppl 6:003. doi: 10.4172/2157-2518.S6-003. J Carcinog Mutagen. 2013. PMID: 25379355 Free PMC article.
The Ripoptosome contains receptor-interacting protein-1/Receptor-Interacting Protein-3 (RIP1), caspase-8, caspase-10, FADD, and c-FLIP isoforms involved in switching apoptotic and necroptotic cell death. c-FLIP regulates the Ripoptosome; in addition to …
The Ripoptosome contains receptor-interacting protein-1/Receptor-Interacting Protein-3 (RIP1), caspase-8, caspase-10, FADD, and c-FLIP …
Pick your poison: the Ripoptosome, a cell death platform regulating apoptosis and necroptosis.
Feoktistova M, Geserick P, Panayotova-Dimitrova D, Leverkus M. Feoktistova M, et al. Cell Cycle. 2012 Feb 1;11(3):460-7. doi: 10.4161/cc.11.3.19060. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22274400
At an unbelievable pace, recent evidence has emerged that demonstrates the importance of a programmed form of necrosis (necroptosis) in physiology, pathophysiology and embryonic development. It is clear that the understanding of the intracellular control of necro …
At an unbelievable pace, recent evidence has emerged that demonstrates the importance of a programmed form of necrosis (necroptosis) …