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21 results

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Page 1
Interleukin-38 is a negative regulator of trained immunity-A retrospective multi-omics study.
Teufel LU, Matzaraki V, Folkman L, de Graaf DM, Horst RT, Moorlag SJCFM, Dos Santos JC, Mulders-Manders CM, Krausgruber T, Dinarello C, Netea MG, Joosten LAB, Arts RJW. Teufel LU, et al. Among authors: folkman l. iScience. 2025 Oct 14;28(11):113758. doi: 10.1016/j.isci.2025.113758. eCollection 2025 Nov 21. iScience. 2025. PMID: 41280669 Free PMC article.
Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation.
Traxler P, Reichl S, Folkman L, Shaw L, Fife V, Nemc A, Pasajlic D, Kusienicka A, Barreca D, Fortelny N, Rendeiro AF, Halbritter F, Weninger W, Decker T, Farlik M, Bock C. Traxler P, et al. Among authors: folkman l. Cell Syst. 2025 Aug 20;16(8):101346. doi: 10.1016/j.cels.2025.101346. Epub 2025 Aug 8. Cell Syst. 2025. PMID: 40782800 Free article.
Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges.
Turina P, Petrosino M, Enriquez Sandoval CA, Novak L, Pasquo A, Alexov E, Alladin MA, Ascher DB, Babbi G, Bakolitsa C, Casadio R, Cheng J, Fariselli P, Folkman L, Kamandula A, Katsonis P, Li M, Li D, Lichtarge O, Mahmud S, Martelli PL, Pal D, Panday SK, Pires DEV, Portelli S, Pucci F, Rodrigues CHM, Rooman M, Savojardo C, Schwersensky M, Shen Y, Strokach AV, Sun Y, Woo J, Radivojac P, Brenner SE, Chiaraluce R, Consalvi V, Capriotti E. Turina P, et al. Among authors: folkman l. Hum Genet. 2025 Mar;144(2-3):265-280. doi: 10.1007/s00439-024-02724-8. Epub 2025 Feb 20. Hum Genet. 2025. PMID: 39976676 Free PMC article.
Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges.
Turina P, Dal Cortivo G, Enriquez Sandoval CA, Alexov E, Ascher DB, Babbi G, Bakolitsa C, Casadio R, Fariselli P, Folkman L, Kamandula A, Katsonis P, Li D, Lichtarge O, Martelli PL, Panday SK, Pires DEV, Portelli S, Pucci F, Rodrigues CHM, Rooman M, Savojardo C, Schwersensky M, Shen Y, Strokach AV, Sun Y, Woo J, Radivojac P, Brenner SE, Dell'Orco D, Capriotti E. Turina P, et al. Among authors: folkman l. Hum Genet. 2025 Mar;144(2-3):113-125. doi: 10.1007/s00439-024-02720-y. Epub 2024 Dec 23. Hum Genet. 2025. PMID: 39714488 Free PMC article.
Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.
Moorlag SJCFM, Folkman L, Ter Horst R, Krausgruber T, Barreca D, Schuster LC, Fife V, Matzaraki V, Li W, Reichl S, Mourits VP, Koeken VACM, de Bree LCJ, Dijkstra H, Lemmers H, van Cranenbroek B, van Rijssen E, Koenen HJPM, Joosten I, Xu CJ, Li Y, Joosten LAB, van Crevel R, Netea MG, Bock C. Moorlag SJCFM, et al. Among authors: folkman l. Immunity. 2024 Jan 9;57(1):171-187.e14. doi: 10.1016/j.immuni.2023.12.005. Immunity. 2024. PMID: 38198850 Free article.
Circadian rhythm influences induction of trained immunity by BCG vaccination.
de Bree LCJ, Mourits VP, Koeken VA, Moorlag SJ, Janssen R, Folkman L, Barreca D, Krausgruber T, Fife-Gernedl V, Novakovic B, Arts RJ, Dijkstra H, Lemmers H, Bock C, Joosten LA, van Crevel R, Benn CS, Netea MG. de Bree LCJ, et al. Among authors: folkman l. J Clin Invest. 2020 Oct 1;130(10):5603-5617. doi: 10.1172/JCI133934. J Clin Invest. 2020. PMID: 32692732 Free PMC article.
Assessment of predicted enzymatic activity of α-N-acetylglucosaminidase variants of unknown significance for CAGI 2016.
Clark WT, Kasak L, Bakolitsa C, Hu Z, Andreoletti G, Babbi G, Bromberg Y, Casadio R, Dunbrack R, Folkman L, Ford CT, Jones D, Katsonis P, Kundu K, Lichtarge O, Martelli PL, Mooney SD, Nodzak C, Pal LR, Radivojac P, Savojardo C, Shi X, Zhou Y, Uppal A, Xu Q, Yin Y, Pejaver V, Wang M, Wei L, Moult J, Yu GK, Brenner SE, LeBowitz JH. Clark WT, et al. Among authors: folkman l. Hum Mutat. 2019 Sep;40(9):1519-1529. doi: 10.1002/humu.23875. Hum Mutat. 2019. PMID: 31342580 Free PMC article.
21 results