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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1988 2
1989 1
1990 6
1991 5
1992 2
1993 11
1994 12
1995 12
1996 7
1997 4
1998 4
1999 8
2000 6
2001 11
2002 6
2003 2
2004 7
2005 11
2006 6
2007 12
2008 9
2009 6
2010 7
2011 5
2012 10
2013 9
2014 4
2015 4
2016 2
2017 2
2018 1
2019 3
2020 4
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186 results
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Page 1
[Epidermal aging and anti-aging strategies].
Wohlrab J, Hilpert K, Wolff L. Wohlrab J, et al. Hautarzt. 2016 Feb;67(2):107-11. doi: 10.1007/s00105-015-3734-6. Hautarzt. 2016. PMID: 26636143 Review. German.
Signs of cellular senescence are reduced proliferation of keratinocytes, cumulation of dysplastic keratinocytes, various mutations (e.g., c-Fos/c-Jun, STAT3, FoxO1), as well as multiple lipid or amino acid metabolic aberrations (e.g., production of advanced g …
Signs of cellular senescence are reduced proliferation of keratinocytes, cumulation of dysplastic keratinocytes, various mutat …
Piperonylic acid stimulates keratinocyte growth and survival by activating epidermal growth factor receptor (EGFR).
Lee D, Lim J, Woo KC, Kim KT. Lee D, et al. Sci Rep. 2018 Jan 9;8(1):162. doi: 10.1038/s41598-017-18361-3. Sci Rep. 2018. PMID: 29317682 Free PMC article.
Epidermal growth factor (EGF) stimulates cell growth, proliferation, and survival. ...The activated signaling pathway eventually up-regulated gene expression of egr-1, c-fos, c-jun, and c-myc, which are involved in cell growth and survival. ...
Epidermal growth factor (EGF) stimulates cell growth, proliferation, and survival. ...The activated signaling pathway eventually up-r
Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis.
Ye F, Zeng Q, Dan G, Dong X, Chen M, Sai Y, Lin H, Zou Z. Ye F, et al. Toxicol Lett. 2020 Feb 1;319:256-263. doi: 10.1016/j.toxlet.2019.10.006. Epub 2019 Oct 19. Toxicol Lett. 2020. PMID: 31639410
Transcription factor activator protein (AP)-1 can be activated in nitrogen-mustard-injured mouse skin, and is thought to participate in the inflammatory response. AP-1 consists of homo- or heterodimers of Fos [c-Fos, Fos-B, fos-related antigen (Fra)-1 …
Transcription factor activator protein (AP)-1 can be activated in nitrogen-mustard-injured mouse skin, and is thought to participate in the …
Identification of Key Genes and Pathways in Cervical Cancer by Bioinformatics Analysis.
Wu X, Peng L, Zhang Y, Chen S, Lei Q, Li G, Zhang C. Wu X, et al. Int J Med Sci. 2019 Jun 2;16(6):800-812. doi: 10.7150/ijms.34172. eCollection 2019. Int J Med Sci. 2019. PMID: 31337953 Free PMC article.
GO analysis suggested that the up-regulated DEGs were mainly enriched in mitotic cell cycle processes, including DNA replication, organelle fission, chromosome segregation and cell cycle phase transition, and that the down-regulated DEGs were primarily enriched in development and …
GO analysis suggested that the up-regulated DEGs were mainly enriched in mitotic cell cycle processes, including DNA replication, organelle …
Influence of genistein on c-Jun, c-Fos and Fos-B of AP-1 subunits expression in skin keratinocytes, fibroblasts and keloid fibroblasts cultured in vitro.
Jurzak M, Adamczyk K. Jurzak M, et al. Acta Pol Pharm. 2013 Mar-Apr;70(2):205-13. Acta Pol Pharm. 2013. PMID: 23614275 Free article.
The aim of the study was to investigate genistein as a potential regulator of C-JUN, C-FOS and FOS-B of AP-1 subunits expression in skin keratinocytes, fibroblasts and keloid fibroblasts cultured in vitro. In presented study, genistein modulated C-JUN express …
The aim of the study was to investigate genistein as a potential regulator of C-JUN, C-FOS and FOS-B of AP-1 subunits expressi …
Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease.
Benhadou F, Glitzner E, Brisebarre A, Swedlund B, Song Y, Dubois C, Rozzi M, Paulissen C, Del Marmol V, Sibilia M, Blanpain C. Benhadou F, et al. Sci Adv. 2020 Jan 8;6(2):eaax5849. doi: 10.1126/sciadv.aax5849. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31934626 Free PMC article.
It remains unclear whether the first events that initiate psoriasis development occur in keratinocytes or inflammatory cells. Here, using different psoriasis mouse models, we showed that conditional deletion of Flt1 or Nrp1 in epidermal cells inhibited psoriasis med …
It remains unclear whether the first events that initiate psoriasis development occur in keratinocytes or inflammatory cells. Here, u …
AP1 transcription factors in epidermal differentiation and skin cancer.
Eckert RL, Adhikary G, Young CA, Jans R, Crish JF, Xu W, Rorke EA. Eckert RL, et al. J Skin Cancer. 2013;2013:537028. doi: 10.1155/2013/537028. Epub 2013 May 23. J Skin Cancer. 2013. PMID: 23762562 Free PMC article.
AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal keratinocyte survival and differentiation and important drivers of cancer development. ...Various in vivo genetic approaches have bee …
AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal
Expression of Bcl-2, p53, c-jun and c-fos protooncogenes in keloids and hypertrophic scars.
Teofoli P, Barduagni S, Ribuffo M, Campanella A, De Pita' O, Puddu P. Teofoli P, et al. J Dermatol Sci. 1999 Dec;22(1):31-7. doi: 10.1016/s0923-1811(99)00040-7. J Dermatol Sci. 1999. PMID: 10651227
Both protooncogenes have been shown to play a role in tissue homeostasis as apoptotic regulatory genes. The c-jun and c-fos protooncogenes are transactivating factors also involved in fibroblast proliferation. ...No protooncogene expression in morphea patients and normal s …
Both protooncogenes have been shown to play a role in tissue homeostasis as apoptotic regulatory genes. The c-jun and c-fos protoonco …
Effect of 1,25 dihydroxyvitamin D3 and calcium on growth and differentiation and on c-fos and p53 gene expression in normal human keratinocytes.
Sebag M, Gulliver W, Kremer R. Sebag M, et al. J Invest Dermatol. 1994 Sep;103(3):323-9. doi: 10.1111/1523-1747.ep12394802. J Invest Dermatol. 1994. PMID: 8077697 Free article.
Calcium enhances keratinocyte differentiation, and 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is both antiproliferative and prodifferentiative in many cell types, including normal human keratinocytes. ...When 1,25(OH)2D3 was added to quiescent keratinocytes, ther …
Calcium enhances keratinocyte differentiation, and 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is both antiproliferative and prodifferenti …
Differential expression of the fos and jun family members c-fos, fosB, Fra-1, Fra-2, c-jun, junB and junD during human epidermal keratinocyte differentiation.
Welter JF, Eckert RL. Welter JF, et al. Oncogene. 1995 Dec 21;11(12):2681-7. Oncogene. 1995. PMID: 8545126
In the present study we describe the localization of c-fos, fosB, Fra-1, Fra-2, c-jun, junB and junD in the normal human epidermis. Each is expressed in specific epidermal layers. c-fos is localized in the nuclei of the upper spinous and granular layer …
In the present study we describe the localization of c-fos, fosB, Fra-1, Fra-2, c-jun, junB and junD in the normal human epidermis
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