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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1988 2
1989 1
1990 6
1991 5
1992 2
1993 11
1994 12
1995 12
1996 7
1997 4
1998 4
1999 8
2000 6
2001 11
2002 6
2003 2
2004 7
2005 11
2006 6
2007 12
2008 9
2009 6
2010 7
2011 5
2012 10
2013 9
2014 4
2015 4
2016 2
2017 2
2018 1
2019 3
2020 4
2021 3
2022 1
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190 results
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Page 1
Isoprocurcumenol Supports Keratinocyte Growth and Survival through Epidermal Growth Factor Receptor Activation.
Kwon PK, Kim SW, De R, Jeong SW, Kim KT. Kwon PK, et al. Int J Mol Sci. 2021 Nov 22;22(22):12579. doi: 10.3390/ijms222212579. Int J Mol Sci. 2021. PMID: 34830467 Free PMC article.
Although proliferation of keratinocytes, a major type of skin cells, is a key factor in maintaining the function of skin, their ability to proliferate tends to diminish with age. ...It increased the phosphorylation of ERK and AKT, and upregulated the expression of genes re …
Although proliferation of keratinocytes, a major type of skin cells, is a key factor in maintaining the function of skin, their abili …
Identification of Key Genes and Pathways in Cervical Cancer by Bioinformatics Analysis.
Wu X, Peng L, Zhang Y, Chen S, Lei Q, Li G, Zhang C. Wu X, et al. Int J Med Sci. 2019 Jun 2;16(6):800-812. doi: 10.7150/ijms.34172. eCollection 2019. Int J Med Sci. 2019. PMID: 31337953 Free PMC article.
GO analysis suggested that the up-regulated DEGs were mainly enriched in mitotic cell cycle processes, including DNA replication, organelle fission, chromosome segregation and cell cycle phase transition, and that the down-regulated DEGs were primarily enriched in development and …
GO analysis suggested that the up-regulated DEGs were mainly enriched in mitotic cell cycle processes, including DNA replication, organelle …
[Epidermal aging and anti-aging strategies].
Wohlrab J, Hilpert K, Wolff L. Wohlrab J, et al. Hautarzt. 2016 Feb;67(2):107-11. doi: 10.1007/s00105-015-3734-6. Hautarzt. 2016. PMID: 26636143 Review. German.
Signs of cellular senescence are reduced proliferation of keratinocytes, cumulation of dysplastic keratinocytes, various mutations (e.g., c-Fos/c-Jun, STAT3, FoxO1), as well as multiple lipid or amino acid metabolic aberrations (e.g., production of advanced g …
Signs of cellular senescence are reduced proliferation of keratinocytes, cumulation of dysplastic keratinocytes, various mutat …
Piperonylic acid stimulates keratinocyte growth and survival by activating epidermal growth factor receptor (EGFR).
Lee D, Lim J, Woo KC, Kim KT. Lee D, et al. Sci Rep. 2018 Jan 9;8(1):162. doi: 10.1038/s41598-017-18361-3. Sci Rep. 2018. PMID: 29317682 Free PMC article.
Epidermal growth factor (EGF) stimulates cell growth, proliferation, and survival. ...The activated signaling pathway eventually up-regulated gene expression of egr-1, c-fos, c-jun, and c-myc, which are involved in cell growth and survival. ...
Epidermal growth factor (EGF) stimulates cell growth, proliferation, and survival. ...The activated signaling pathway eventually up-r
Syndecan-1 shedding by meprin β impairs keratinocyte adhesion and differentiation in hyperkeratosis.
Peters F, Rahn S, Mengel M, Scharfenberg F, Otte A, Koudelka T, Wagner EF, Wunderlich FT, Haase M, Naumann R, Tholey A, Becker-Pauly C. Peters F, et al. Matrix Biol. 2021 Aug;102:37-69. doi: 10.1016/j.matbio.2021.08.002. Epub 2021 Sep 8. Matrix Biol. 2021. PMID: 34508852
Dysregulation of proteolytic enzymes has huge impact on epidermal homeostasis, which can result in severe pathological conditions such as fibrosis or Netherton syndrome. ...Interestingly, induced meprin beta expression in the epidermis resulted in hyperkeratosis, ha …
Dysregulation of proteolytic enzymes has huge impact on epidermal homeostasis, which can result in severe pathological conditions suc …
AP1 transcription factors in epidermal differentiation and skin cancer.
Eckert RL, Adhikary G, Young CA, Jans R, Crish JF, Xu W, Rorke EA. Eckert RL, et al. J Skin Cancer. 2013;2013:537028. doi: 10.1155/2013/537028. Epub 2013 May 23. J Skin Cancer. 2013. PMID: 23762562 Free PMC article.
AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal keratinocyte survival and differentiation and important drivers of cancer development. ...Various in vivo genetic approaches have bee …
AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal
Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis.
Ye F, Zeng Q, Dan G, Dong X, Chen M, Sai Y, Lin H, Zou Z. Ye F, et al. Toxicol Lett. 2020 Feb 1;319:256-263. doi: 10.1016/j.toxlet.2019.10.006. Epub 2019 Oct 19. Toxicol Lett. 2020. PMID: 31639410
Transcription factor activator protein (AP)-1 can be activated in nitrogen-mustard-injured mouse skin, and is thought to participate in the inflammatory response. AP-1 consists of homo- or heterodimers of Fos [c-Fos, Fos-B, fos-related antigen (Fra)-1 …
Transcription factor activator protein (AP)-1 can be activated in nitrogen-mustard-injured mouse skin, and is thought to participate in the …
N-methyl-d-aspartate receptor subunit 2B on keratinocyte mediates peripheral and central sensitization in chronic post-ischemic pain in male rats.
Xu X, Tao X, Huang P, Lin F, Liu Q, Xu L, Xu J, Huang Y. Xu X, et al. Brain Behav Immun. 2020 Jul;87:579-590. doi: 10.1016/j.bbi.2020.02.003. Epub 2020 Feb 4. Brain Behav Immun. 2020. PMID: 32032782 Free PMC article.
Central sensitization-related C-fos induction, as well as astrocytes and microglia activation in the spinal cord dorsal horn (SDH) were studied using immunofluorescence. ...CPIP-associated c-fos induction in SDH persisted from acute to chronic stages after ischemia, …
Central sensitization-related C-fos induction, as well as astrocytes and microglia activation in the spinal cord dorsal horn (SDH) we …
TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Wang XJ, Greenhalgh DA, Lu XR, Bickenbach JR, Roop DR. Wang XJ, et al. Oncogene. 1995 Jan 19;10(2):279-89. Oncogene. 1995. PMID: 7530825
To assess the synergistic effect of growth and transcription factor deregulation on carcinogenesis in vivo, mating experiments were performed between transgenic mice expressing human TGF alpha or v-fos exclusively in the epidermis by means of a human keratin K1-base …
To assess the synergistic effect of growth and transcription factor deregulation on carcinogenesis in vivo, mating experiments were performe …
Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos.
Briso EM, Guinea-Viniegra J, Bakiri L, Rogon Z, Petzelbauer P, Eils R, Wolf R, Rincón M, Angel P, Wagner EF. Briso EM, et al. Genes Dev. 2013 Sep 15;27(18):1959-73. doi: 10.1101/gad.223339.113. Epub 2013 Sep 12. Genes Dev. 2013. PMID: 24029918 Free PMC article.
Chronic skin inflammation has been associated with the development of SCCs, but the contribution of skin inflammation to SCC development remains largely unknown. In this study, we demonstrate that inducible expression of c-fos in the epidermis of adult mice is suffi …
Chronic skin inflammation has been associated with the development of SCCs, but the contribution of skin inflammation to SCC development rem …
190 results