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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 2
2002 3
2003 5
2004 14
2005 13
2006 16
2007 24
2008 35
2009 29
2010 35
2011 39
2012 48
2013 48
2014 59
2015 67
2016 73
2017 61
2018 66
2019 74
2020 74
2021 31
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722 results
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Endothelial Foxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 Inflammasome Activation.
Zhuang T, Liu J, Chen X, Zhang L, Pi J, Sun H, Li L, Bauer R, Wang H, Yu Z, Zhang Q, Tomlinson B, Chan P, Zheng X, Morrisey E, Liu Z, Reilly M, Zhang Y. Zhuang T, et al. Circ Res. 2019 Aug 30;125(6):590-605. doi: 10.1161/CIRCRESAHA.118.314402. Epub 2019 Jul 18. Circ Res. 2019. PMID: 31318658
Endothelial-specific Foxp1 knockout mice (Foxp1(ECKO)) were bred onto Apoe(KO) mice to generate endothelial Foxp1-deletion hyperlipidemic model Foxp1(ECKO);Apoe(KO), which displayed significant increases in atherosclerotic lesion formation in aortas an …
Endothelial-specific Foxp1 knockout mice (Foxp1(ECKO)) were bred onto Apoe(KO) mice to generate endothelial Foxp1-delet …
Prospective investigation of FOXP1 syndrome.
Siper PM, De Rubeis S, Trelles MDP, Durkin A, Di Marino D, Muratet F, Frank Y, Lozano R, Eichler EE, Kelly M, Beighley J, Gerdts J, Wallace AS, Mefford HC, Bernier RA, Kolevzon A, Buxbaum JD. Siper PM, et al. Mol Autism. 2017 Oct 24;8:57. doi: 10.1186/s13229-017-0172-6. eCollection 2017. Mol Autism. 2017. PMID: 29090079 Free PMC article.
BACKGROUND: Haploinsufficiency of the forkhead-box protein P1 (FOXP1) gene leads to a neurodevelopmental disorder termed FOXP1 syndrome. ...The genetic findings can be incorporated into clinical genetics practice to improve accurate genetic diagnosis of FOXP1
BACKGROUND: Haploinsufficiency of the forkhead-box protein P1 (FOXP1) gene leads to a neurodevelopmental disorder termed FOXP1
Foxp1 controls brown/beige adipocyte differentiation and thermogenesis through regulating beta3-AR desensitization.
Liu P, Huang S, Ling S, Xu S, Wang F, Zhang W, Zhou R, He L, Xia X, Yao Z, Fan Y, Wang N, Hu C, Zhao X, Tucker HO, Wang J, Guo X. Liu P, et al. Nat Commun. 2019 Nov 7;10(1):5070. doi: 10.1038/s41467-019-12988-8. Nat Commun. 2019. PMID: 31699980 Free PMC article.
Adipose-specific deletion of Foxp1 leads to an increase of brown adipose activity and browning program of white adipose tissues. ...Consistently, overexpression of Foxp1 in adipocytes impairs adaptive thermogenesis and promotes diet-induced obesity. ...
Adipose-specific deletion of Foxp1 leads to an increase of brown adipose activity and browning program of white adipose tissues. ...C …
FOXP1-related intellectual disability syndrome: a recognisable entity.
Meerschaut I, Rochefort D, Revençu N, Pètre J, Corsello C, Rouleau GA, Hamdan FF, Michaud JL, Morton J, Radley J, Ragge N, García-Miñaúr S, Lapunzina P, Bralo MP, Mori MÁ, Moortgat S, Benoit V, Mary S, Bockaert N, Oostra A, Vanakker O, Velinov M, de Ravel TJ, Mekahli D, Sebat J, Vaux KK, DiDonato N, Hanson-Kahn AK, Hudgins L, Dallapiccola B, Novelli A, Tarani L, Andrieux J, Parker MJ, Neas K, Ceulemans B, Schoonjans AS, Prchalova D, Havlovicova M, Hancarova M, Budisteanu M, Dheedene A, Menten B, Dion PA, Lederer D, Callewaert B. Meerschaut I, et al. J Med Genet. 2017 Sep;54(9):613-623. doi: 10.1136/jmedgenet-2017-104579. Epub 2017 Jul 22. J Med Genet. 2017. PMID: 28735298
METHODS: We correlate clinical and molecular data of 25 novel and 23 previously reported patients with FOXP1 defects. We evaluated FOXP1 activity by an in vitro luciferase model and assessed protein stability in vitro by western blotting. ...CONCLUSIONS: FOXP1
METHODS: We correlate clinical and molecular data of 25 novel and 23 previously reported patients with FOXP1 defects. We evaluated …
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
Li H, Liu P, Xu S, Li Y, Dekker JD, Li B, Fan Y, Zhang Z, Hong Y, Yang G, Tang T, Ren Y, Tucker HO, Yao Z, Guo X. Li H, et al. J Clin Invest. 2017 Apr 3;127(4):1241-1253. doi: 10.1172/JCI89511. Epub 2017 Feb 27. J Clin Invest. 2017. PMID: 28240601 Free PMC article.
Loss of p16INK4A in Foxp1-deficient MSCs partially rescued the defects in replication capacity and bone mass accrual. Promoter occupancy analyses revealed that FOXP1 directly represses transcription of p16INK4A. These results indicate that FOXP1 attenuates MS …
Loss of p16INK4A in Foxp1-deficient MSCs partially rescued the defects in replication capacity and bone mass accrual. Promoter occupa …
FOXP1 negatively regulates tumor infiltrating lymphocyte migration in human breast cancer.
De Silva P, Garaud S, Solinas C, de Wind A, Van den Eyden G, Jose V, Gu-Trantien C, Migliori E, Boisson A, Naveaux C, Duvillier H, Craciun L, Larsimont D, Piccart-Gebhart M, Willard-Gallo K. De Silva P, et al. EBioMedicine. 2019 Jan;39:226-238. doi: 10.1016/j.ebiom.2018.11.066. Epub 2018 Dec 20. EBioMedicine. 2019. PMID: 30579865 Free PMC article.
Cytokine and chemokine expression and lymphocyte migration in response to primary tumor supernatants (SN) was compared between FOXP1(hi) and FOXP1(lo) primary BC. FINDING: FOXP1 expression was higher in estrogen receptor positive compared to negative BC. F
Cytokine and chemokine expression and lymphocyte migration in response to primary tumor supernatants (SN) was compared between FOXP1( …
Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function.
Konopacki C, Pritykin Y, Rubtsov Y, Leslie CS, Rudensky AY. Konopacki C, et al. Nat Immunol. 2019 Feb;20(2):232-242. doi: 10.1038/s41590-018-0291-z. Epub 2019 Jan 14. Nat Immunol. 2019. PMID: 30643266 Free PMC article.
Regulatory T cells (T(reg) cells), whose differentiation and function are controlled by transcription factor Foxp3, express the closely related family member Foxp1. Here we explored Foxp1 function in T(reg) cells. We found that a large number of Foxp3-bound genomic …
Regulatory T cells (T(reg) cells), whose differentiation and function are controlled by transcription factor Foxp3, express the closely rela …
Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function.
Ren J, Han L, Tang J, Liu Y, Deng X, Liu Q, Hao P, Feng X, Li B, Hu H, Wang H. Ren J, et al. PLoS Biol. 2019 May 24;17(5):e3000270. doi: 10.1371/journal.pbio.3000270. eCollection 2019 May. PLoS Biol. 2019. PMID: 31125332 Free PMC article.
Furthermore, we found that Foxp1 and Foxp3 coordinated the regulation of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) expression levels. Taken together, our study demonstrates that Foxp1 plays critical roles in both maintaining Treg cell quiescence during ho …
Furthermore, we found that Foxp1 and Foxp3 coordinated the regulation of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) express …
miR-29c-3p inhibits autophagy and cisplatin resistance in ovarian cancer by regulating FOXP1/ATG14 pathway.
Hu Z, Cai M, Zhang Y, Tao L, Guo R. Hu Z, et al. Cell Cycle. 2020 Jan;19(2):193-206. doi: 10.1080/15384101.2019.1704537. Epub 2019 Dec 29. Cell Cycle. 2020. PMID: 31885310 Free PMC article.
This study aims to identify the effect of miR-29c-3p/FOXP1/ATG14 pathway in regulating autophagy and DDP resistance in ovarian cancer. ...The anti-resistant effect of miR-29c-3p was observed as overexpressing miR-29c-3p inhibited cell viability of DDP-resistant cells. More …
This study aims to identify the effect of miR-29c-3p/FOXP1/ATG14 pathway in regulating autophagy and DDP resistance in ovarian cancer …
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