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FRAP analysis of binding: proper and fitting.
Sprague BL, McNally JG. Sprague BL, et al. Trends Cell Biol. 2005 Feb;15(2):84-91. doi: 10.1016/j.tcb.2004.12.001. Trends Cell Biol. 2005. PMID: 15695095 Review.
In vivo analyses of these interactions are frequently done using fluorescence recovery after photobleaching (FRAP). Proper interpretation of FRAP data yields information about the binding interactions of fluorescently tagged molecules, including the nu …
In vivo analyses of these interactions are frequently done using fluorescence recovery after photobleaching (FRAP). Proper int …
Combinative effects of akarkara root-derived metabolites on anti-inflammatory and anti-alzheimer key enzymes: integrating bioassay-guided fractionation, GC-MS analysis, and in silico studies.
Ibrahim RM, Abdel-Baki PM, Elmasry GF, El-Rashedy AA, Mahdy NE. Ibrahim RM, et al. BMC Complement Med Ther. 2023 Nov 17;23(1):413. doi: 10.1186/s12906-023-04210-6. BMC Complement Med Ther. 2023. PMID: 37978514 Free PMC article.
They inhibited the secretion of pro-inflammatory cytokines (TNF-alpha, IL-1beta, and IL-6) in activated RAW macrophages. The isolated compounds showed good fitting in the active sites of acetylcholinesterase and COX-2 with high docking scores. ...Molecular dynamics simulat …
They inhibited the secretion of pro-inflammatory cytokines (TNF-alpha, IL-1beta, and IL-6) in activated RAW macrophages. The isolated compou …