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Effect of Race/Ethnicity on United States FRAX Calculations and Treatment Qualification: A Registry-Based Study.
Leslie WD; ASBMR Task Force on Clinical Algorithms for Fracture Risk. Leslie WD, et al. J Bone Miner Res. 2023 Dec;38(12):1742-1748. doi: 10.1002/jbmr.4896. Epub 2023 Nov 10. J Bone Miner Res. 2023. PMID: 37548387 Free article.
Since 2008. the United States has had four race/ethnic fracture risk assessment tool (FRAX) calculators: White ("Caucasian"), Black, Asian, and Hispanic. The American Society for Bone and Mineral Research Task Force on Clinical Algorithms for Fracture …
Since 2008. the United States has had four race/ethnic fracture risk assessment tool (FRAX) calculators: White ( …
Osteoporosis Epidemiology, Diagnosis, and Management Across Race and Ethnicity in the United States.
Dickens LT, Abe CM, Connors M, Osman F, Abdelaziz S, Duge LS, Jain RK. Dickens LT, et al. J Clin Endocrinol Metab. 2025 Nov 18;110(12):3309-3321. doi: 10.1210/clinem/dgaf466. J Clin Endocrinol Metab. 2025. PMID: 40820822 Review.
Osteoporosis epidemiology, diagnosis, and management all are influenced by race and ethnicity. Studies have found approximately 40% to 50% lower fracture rates in Black and Asian as compared to White women. ...The diagnosis of osteoporosis can be made by prior fragility fr …
Osteoporosis epidemiology, diagnosis, and management all are influenced by race and ethnicity. Studies have found approximately 40% t …
FRAX updates 2016.
McCloskey EV, Harvey NC, Johansson H, Kanis JA. McCloskey EV, et al. Curr Opin Rheumatol. 2016 Jul;28(4):433-41. doi: 10.1097/BOR.0000000000000304. Curr Opin Rheumatol. 2016. PMID: 27163858 Review.
Although the core of the fracture risk algorithm remains unchanged, there is growing evidence of possible additional independent clinical variables that might modulate the interpretation of the FRAX outputs. There is also an expanding number of international guidelines tha …
Although the core of the fracture risk algorithm remains unchanged, there is growing evidence of possible additional independent clinical va …
Worldwide Fracture Prediction.
El-Hajj Fuleihan G, Chakhtoura M, Cauley JA, Chamoun N. El-Hajj Fuleihan G, et al. J Clin Densitom. 2017 Jul-Sep;20(3):397-424. doi: 10.1016/j.jocd.2017.06.008. Epub 2017 Jul 19. J Clin Densitom. 2017. PMID: 28734709 Review.
These include Osteoporosis Self-Assessment Tool; Osteoporosis Risk Assessment Instrument; Simple Calculated Osteoporosis Risk Estimation; Canadian Association of Radiologists and Osteoporosis Canada calculator; Fracture Risk Assessment Calculator (FRAX); Garvan; and QFract …
These include Osteoporosis Self-Assessment Tool; Osteoporosis Risk Assessment Instrument; Simple Calculated Osteoporosis Risk Estimation; Ca …
An Update on the Fracture Risk Assessment Tool: What Have We Learned over 15+ years?
Dickens LT, Jain RK. Dickens LT, et al. Endocrinol Metab Clin North Am. 2024 Dec;53(4):531-545. doi: 10.1016/j.ecl.2024.08.001. Epub 2024 Sep 10. Endocrinol Metab Clin North Am. 2024. PMID: 39448135 Review.
FRAX has been incorporated into clinical treatment guidelines and is well validated in specific disease states like chronic kidney disease. However, there are risk factors which are not captured by FRAX such as diabetes and falls. The use of race-ethnicity …
FRAX has been incorporated into clinical treatment guidelines and is well validated in specific disease states like chronic ki …
Osteoporosis and Fracture Risk among Older US Asian Adults.
Lo JC, Yang W, Park-Sigal JJ, Ott SM. Lo JC, et al. Curr Osteoporos Rep. 2023 Oct;21(5):592-608. doi: 10.1007/s11914-023-00805-7. Epub 2023 Aug 5. Curr Osteoporos Rep. 2023. PMID: 37542683 Free PMC article. Review.
The latter may relate to favorable characteristics in hip geometry, volumetric bone density, and bone microarchitecture; lower risk of falls; and other clinical factors. The fracture risk calculator FRAX accounts for the lower risk of hip fracture among US Asian adults. Ho …
The latter may relate to favorable characteristics in hip geometry, volumetric bone density, and bone microarchitecture; lower risk of falls …
The American Society for Bone and Mineral Research Task Force on clinical algorithms for fracture risk report.
Burnett-Bowie SM, Wright NC, Yu EW, Langsetmo L, Yearwood GMH, Crandall CJ, Leslie WD, Cauley JA. Burnett-Bowie SM, et al. J Bone Miner Res. 2024 May 24;39(5):517-530. doi: 10.1093/jbmr/zjae048. J Bone Miner Res. 2024. PMID: 38590141
The Task Force reviewed the historical development of FRAX, including the assumptions underlying selection of race and ethnicity adjustment factors. Furthermore, a systematic review of literature was conducted, which revealed an overall paucity of data evaluating th …
The Task Force reviewed the historical development of FRAX, including the assumptions underlying selection of race and ethnicity …
Utility of Trabecular Bone Score in the Management of Patients with Osteoporosis.
Lewiecki EM. Lewiecki EM. Endocrinol Metab Clin North Am. 2024 Dec;53(4):547-557. doi: 10.1016/j.ecl.2024.07.001. Epub 2024 Aug 30. Endocrinol Metab Clin North Am. 2024. PMID: 39448136 Review.
Trabecular bone score (TBS) enhances assessment of fracture risk in older women and men across many race/ethnicities and with a broad range of comorbidities. The best validated clinical utility of TBS is for input in the FRAX algorithm to modify assessment of fractu …
Trabecular bone score (TBS) enhances assessment of fracture risk in older women and men across many race/ethnicities and with a broad …
Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific region.
Wu CH, McCloskey EV, Lee JK, Itabashi A, Prince R, Yu W, Li-Yu J, Chionh SB, Zhao Y, Shin CS, Gunawan T, Tsai KS, Chieng PU, Changlai SP, Chan DC, Chen JF, Tanner SB, Hans DB, Kanis JA, Chang YF, Sun ZJ, Yang RS; Asia Pacific Panel of ISCD. Wu CH, et al. J Clin Densitom. 2014 Jan-Mar;17(1):150-5. doi: 10.1016/j.jocd.2013.06.002. Epub 2013 Jul 31. J Clin Densitom. 2014. PMID: 23916756
FRAX models are not yet available for all countries or ethnicities, but surrogate models can be used within regions with similar fracture risk. ...Their visions are to advance the awareness, education, prevention, and treatment of osteoporosis. In November 2010, the …
FRAX models are not yet available for all countries or ethnicities, but surrogate models can be used within regions with simil …
Hip Fracture Risk Assessment Tools for Adults Aged 80 Years and Older.
Ensrud KE, Schousboe JT, Crandall CJ, Leslie WD, Fink HA, Cawthon PM, Kado DM, Lane NE, Cauley JA, Langsetmo L. Ensrud KE, et al. JAMA Netw Open. 2024 Jun 3;7(6):e2418612. doi: 10.1001/jamanetworkopen.2024.18612. JAMA Netw Open. 2024. PMID: 38941095 Free PMC article.
Among women, AUC was 0.69 (95% CI, 0.67-0.72) for FRAX, 0.69 (95% CI, 0.66-0.72) for Garvan, and 0.72 (95% CI, 0.69-0.75) for FNBMD alone (FNBMD superior to FRAX, P = .01; and Garvan, P = .01). Among men, AUC was 0.71 (95% CI, 0.66-0.75) for FRAX, 0.76 (95% C …
Among women, AUC was 0.69 (95% CI, 0.67-0.72) for FRAX, 0.69 (95% CI, 0.66-0.72) for Garvan, and 0.72 (95% CI, 0.69-0.75) for FNBMD a …
48 results