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Year Number of Results
2009 1
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39 results

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Page 1
The clinician's guide to prevention and treatment of osteoporosis.
LeBoff MS, Greenspan SL, Insogna KL, Lewiecki EM, Saag KG, Singer AJ, Siris ES. LeBoff MS, et al. Osteoporos Int. 2022 Oct;33(10):2049-2102. doi: 10.1007/s00198-021-05900-y. Epub 2022 Apr 28. Osteoporos Int. 2022. PMID: 35478046 Free PMC article.
Osteoporosis detection, diagnosis, and treatment should be routine practice in all adult healthcare settings. The Bone Health and Osteoporosis Foundation (BHOF) - formerly the National Osteoporosis Foundation - first published the Clinician's Guide in 1999 to provide accur …
Osteoporosis detection, diagnosis, and treatment should be routine practice in all adult healthcare settings. The Bone Health and Ost …
An optimal intervention threshold of FRAX in postmenopausal Thai women.
Sribenjalak D, Charoensri S, Pongchaiyakul C. Sribenjalak D, et al. Arch Osteoporos. 2022 Jan 24;17(1):21. doi: 10.1007/s11657-022-01058-0. Arch Osteoporos. 2022. PMID: 35072805
This study was designed to determine a FRAX intervention threshold in postmenopausal Thais, based on a history of hip fracture. ...The proposed threshold should be considered as new cutoff for initiating osteoporosis treatment in postmenopaus …
This study was designed to determine a FRAX intervention threshold in postmenopausal Thais, based on a history of hip f …
Setting the new FRAX reference threshold without bone mineral density in Chinese postmenopausal women.
Liu S, Chen R, Ding N, Wang Q, Huang M, Liu H, Xie Z, Ou Y, Sheng Z. Liu S, et al. J Endocrinol Invest. 2021 Feb;44(2):347-352. doi: 10.1007/s40618-020-01315-4. Epub 2020 Jun 3. J Endocrinol Invest. 2021. PMID: 32495298
In this study, we explored the Chinese-specific thresholds of FRAX without the T-score. METHODS: In all, 264 postmenopausal women aged > 50 years were randomly recruited from community-medical centers. ...CONCLUSION: Current guideline-recommended …
In this study, we explored the Chinese-specific thresholds of FRAX without the T-score. METHODS: In all, 264 postmen …
Bayesian Genome-wide Polygenic Score Integration with FRAX for Enhanced Fracture Risk Prediction in Postmenopausal Women.
Liu A, Liu J, Wu Q. Liu A, et al. medRxiv [Preprint]. 2025 Jun 7:2025.06.06.25329139. doi: 10.1101/2025.06.06.25329139. medRxiv. 2025. PMID: 40502616 Free PMC article. Preprint.
OBJECTIVE: To develop and validate a novel genome-informed fracture risk assessment tool (Bayes-FRAX) integrating Bayesian genome-wide polygenic scores (GPS) into the established FRAX to enhance major osteoporotic fracture (MOF) prediction. ...Bayes-FRAX …
OBJECTIVE: To develop and validate a novel genome-informed fracture risk assessment tool (Bayes-FRAX) integrating Bayesian genome-wid …
Individualizing osteoporosis medications.
Silverman S. Silverman S. Menopause. 2014 Mar;21(3):306-8. doi: 10.1097/GME.0000000000000180. Menopause. 2014. PMID: 24518155
Mrs. JD is a 58-year-old postmenopausal woman having symptoms of hot flashes and night sweats. She has a dual-energy x-ray absorptiometry T-score of -2.4 in the femoral neck, consistent with low bone mass or osteopenia. She has a parental history of hip fracture. …
Mrs. JD is a 58-year-old postmenopausal woman having symptoms of hot flashes and night sweats. She has a dual-energy x-ray absorptiom …
FRAX-based intervention and assessment thresholds for osteoporosis in Iran.
Khashayar P, Keshtkar A, Ostovar A, Larijani B, Johansson H, Harvey NC, Lorentzon M, McCloskey E, Kanis JA. Khashayar P, et al. Osteoporos Int. 2019 Nov;30(11):2225-2230. doi: 10.1007/s00198-019-05078-4. Epub 2019 Aug 1. Osteoporos Int. 2019. PMID: 31372709
We compared the utility of the current Iranian guidelines that recommend treatment in women with a T-score - 2.5 SD with a FRAX-based intervention threshold equivalent to women of average BMI with a prior fragility fracture. Whereas the FRAX-b …
We compared the utility of the current Iranian guidelines that recommend treatment in women with a T-score - 2.5 SD with a …
Postmenopausal Osteoporosis: From Molecular Pathways to Therapeutic Targets-A Mechanism-to-Practice Framework Integrating Pharmacotherapy, Fall Prevention, and Adherence into Patient-Centered Care.
Ena G, Soyfoo M. Ena G, et al. J Clin Med. 2025 Dec 23;15(1):102. doi: 10.3390/jcm15010102. J Clin Med. 2025. PMID: 41517353 Free PMC article. Review.
Beyond drug selection, we examine the persistent treatment gap in which fewer than 20% of post-fracture patients receive therapy, arguing that fall prevention-responsible for >90% of hip fractures-and medication adherence deserve equal priority in clinical practi …
Beyond drug selection, we examine the persistent treatment gap in which fewer than 20% of post-fracture patients receive therapy …
Utility of trabecular bone score in the evaluation of osteoporosis.
Martineau P, Silva BC, Leslie WD. Martineau P, et al. Curr Opin Endocrinol Diabetes Obes. 2017 Dec;24(6):402-410. doi: 10.1097/MED.0000000000000365. Curr Opin Endocrinol Diabetes Obes. 2017. PMID: 28857846 Review.
RECENT FINDINGS: TBS-adjusted The Fracture Risk Assessment tool (FRAX) probabilities enhance fracture risk prediction compared with conventional FRAX predictions. TBS has been found to better categorize fracture risk and assists in FRAX-based treatment …
RECENT FINDINGS: TBS-adjusted The Fracture Risk Assessment tool (FRAX) probabilities enhance fracture risk prediction compared with c …
The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis.
Borgström F, Ström O, Coelho J, Johansson H, Oden A, McCloskey E, Kanis JA. Borgström F, et al. Osteoporos Int. 2010 Feb;21(2):339-49. doi: 10.1007/s00198-009-0971-5. Epub 2009 Jun 10. Osteoporos Int. 2010. PMID: 19513577
INTRODUCTION: The objectives of the study were to estimate the cost-effectiveness of strontium ranelate in the UK for the treatment of osteoporosis and to establish intervention thresholds for treatment using the FRAX tool. METHODS: The cost-effectiven …
INTRODUCTION: The objectives of the study were to estimate the cost-effectiveness of strontium ranelate in the UK for the treatment o …
Effect of FRAXplus adjustments on fracture risk reclassification in older Swedish women-results from the SUPERB-study.
Zoulakis M, Johansson H, Harvey NC, Axelsson KF, Litsne H, Johansson L, Schini M, Vandenput L, McCloskey EV, Kanis JA, Lorentzon M. Zoulakis M, et al. Osteoporos Int. 2025 Sep;36(9):1649-1659. doi: 10.1007/s00198-025-07588-w. Epub 2025 Jul 11. Osteoporos Int. 2025. PMID: 40643676 Free PMC article.
FRAXplus facilitates adjustment of FRAX fracture probabilities for additional clinical risk factors. This study examined how FRAXplus adjustments affect the proportion of older Swedish women eligible for treatment at a major osteoporotic fracture (MOF) probability …
FRAXplus facilitates adjustment of FRAX fracture probabilities for additional clinical risk factors. This study examined how FRAXpl …
39 results