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Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.
Fagerlund RD, Wilkinson ME, Klykov O, Barendregt A, Pearce FG, Kieper SN, Maxwell HWR, Capolupo A, Heck AJR, Krause KL, Bostina M, Scheltema RA, Staals RHJ, Fineran PC. Fagerlund RD, et al. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5122-E5128. doi: 10.1073/pnas.1618421114. Epub 2017 Jun 13. Proc Natl Acad Sci U S A. 2017. PMID: 28611213 Free PMC article.
CRISPR-Cas: Adapting to change.
Jackson SA, McKenzie RE, Fagerlund RD, Kieper SN, Fineran PC, Brouns SJ. Jackson SA, et al. Among authors: fagerlund rd. Science. 2017 Apr 7;356(6333):eaal5056. doi: 10.1126/science.aal5056. Epub 2017 Apr 6. Science. 2017. PMID: 28385959 Review.
The autoregulator Aca2 mediates anti-CRISPR repression.
Birkholz N, Fagerlund RD, Smith LM, Jackson SA, Fineran PC. Birkholz N, et al. Among authors: fagerlund rd. Nucleic Acids Res. 2019 Oct 10;47(18):9658-9665. doi: 10.1093/nar/gkz721. Nucleic Acids Res. 2019. PMID: 31428783 Free PMC article.
Expanding the mass range for UVPD-based native top-down mass spectrometry.
Greisch JF, Tamara S, Scheltema RA, Maxwell HWR, Fagerlund RD, Fineran PC, Tetter S, Hilvert D, Heck AJR. Greisch JF, et al. Among authors: fagerlund rd. Chem Sci. 2019 Jul 1;10(30):7163-7171. doi: 10.1039/c9sc01857c. eCollection 2019 Aug 14. Chem Sci. 2019. PMID: 31588283 Free PMC article.
Crystal structure of the anti-CRISPR repressor Aca2.
Usher B, Birkholz N, Beck IN, Fagerlund RD, Jackson SA, Fineran PC, Blower TR. Usher B, et al. Among authors: fagerlund rd. J Struct Biol. 2021 Sep;213(3):107752. doi: 10.1016/j.jsb.2021.107752. Epub 2021 Jun 8. J Struct Biol. 2021. PMID: 34116143 Free PMC article.
28 results