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Role of proinflammatory cytokines in the pathophysiology of osteoarthritis.
Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H. Kapoor M, et al. Among authors: fahmi h. Nat Rev Rheumatol. 2011 Jan;7(1):33-42. doi: 10.1038/nrrheum.2010.196. Epub 2010 Nov 30. Nat Rev Rheumatol. 2011. PMID: 21119608 Review.
Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.
Di Battista JA, Fahmi H, He Y, Zhang M, Martel-Pelletier J, Pelletier JP. Di Battista JA, et al. Among authors: fahmi h. Clin Exp Rheumatol. 2001;19(1 Suppl 22):S3-5. Clin Exp Rheumatol. 2001. PMID: 11296546
Nimesulide reduces interleukin-1beta-induced cyclooxygenase-2 gene expression in human synovial fibroblasts.
Fahmi H, He Y, Zhang M, Martel-Pelletier J, Pelletier JP, Di Battista JA. Fahmi H, et al. Osteoarthritis Cartilage. 2001 May;9(4):332-40. doi: 10.1053/joca.2000.0393. Osteoarthritis Cartilage. 2001. PMID: 11399097
NIM blocked ionomycin+thapsigargin and H(2)O(2)-induced increases in COX-2 protein synthesis. CONCLUSION: NIM inhibits cytokine-induced COX-2 expression and protein at sub and therapeutic concentrations. ...
NIM blocked ionomycin+thapsigargin and H(2)O(2)-induced increases in COX-2 protein synthesis. CONCLUSION: NIM inhibits cytokine-induc …
Cyclooxygenase-2 and prostaglandins in articular tissues.
Martel-Pelletier J, Pelletier JP, Fahmi H. Martel-Pelletier J, et al. Among authors: fahmi h. Semin Arthritis Rheum. 2003 Dec;33(3):155-67. doi: 10.1016/s0049-0172(03)00134-3. Semin Arthritis Rheum. 2003. PMID: 14671726 Review.
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.
Cheng S, Afif H, Martel-Pelletier J, Pelletier JP, Li X, Farrajota K, Lavigne M, Fahmi H. Cheng S, et al. Among authors: fahmi h. J Biol Chem. 2004 May 21;279(21):22057-65. doi: 10.1074/jbc.M402828200. Epub 2004 Mar 15. J Biol Chem. 2004. PMID: 15023995
mPGES-1 as a novel target for arthritis.
Fahmi H. Fahmi H. Curr Opin Rheumatol. 2004 Sep;16(5):623-7. doi: 10.1097/01.bor.0000129664.81052.8e. Curr Opin Rheumatol. 2004. PMID: 15314505 Review.
Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.
Martel-Pelletier J, Mineau F, Fahmi H, Laufer S, Reboul P, Boileau C, Lavigne M, Pelletier JP. Martel-Pelletier J, et al. Among authors: fahmi h. Arthritis Rheum. 2004 Dec;50(12):3925-33. doi: 10.1002/art.20632. Arthritis Rheum. 2004. PMID: 15593193
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.
Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H. Li X, et al. Among authors: fahmi h. J Rheumatol. 2005 May;32(5):887-95. J Rheumatol. 2005. PMID: 15868626
New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets.
Martel-Pelletier J, Lajeunesse D, Fahmi H, Tardif G, Pelletier JP. Martel-Pelletier J, et al. Among authors: fahmi h. Curr Rheumatol Rep. 2006 Feb;8(1):30-6. doi: 10.1007/s11926-006-0022-6. Curr Rheumatol Rep. 2006. PMID: 16515762 Review.
Association of polymorphisms in the peroxisome proliferator-activated receptor gamma gene and osteoarthritis of the knee.
Cheng S, Afif H, Martel-Pelletier J, Benderdour M, Pelletier JP, Hilal G, Haraoui P, Raynauld JP, Choquette D, Fahmi H. Cheng S, et al. Among authors: fahmi h. Ann Rheum Dis. 2006 Oct;65(10):1394-7. doi: 10.1136/ard.2006.051904. Ann Rheum Dis. 2006. PMID: 16973789 Free PMC article.
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