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Mcl-1 is essential for the survival of plasma cells.
Peperzak V, Vikström I, Walker J, Glaser SP, LePage M, Coquery CM, Erickson LD, Fairfax K, Mackay F, Strasser A, Nutt SL, Tarlinton DM. Peperzak V, et al. Among authors: fairfax k. Nat Immunol. 2013 Mar;14(3):290-7. doi: 10.1038/ni.2527. Epub 2013 Feb 3. Nat Immunol. 2013. PMID: 23377201 Free PMC article.
A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.
Amann-Zalcenstein D, Tian L, Schreuder J, Tomei S, Lin DS, Fairfax KA, Bolden JE, McKenzie MD, Jarratt A, Hilton A, Jackson JT, Di Rago L, McCormack MP, de Graaf CA, Stonehouse O, Taoudi S, Alexander WS, Nutt SL, Ritchie ME, Ng AP, Naik SH. Amann-Zalcenstein D, et al. Nat Immunol. 2020 Dec;21(12):1574-1584. doi: 10.1038/s41590-020-0799-x. Epub 2020 Oct 19. Nat Immunol. 2020. PMID: 33077975
FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis.
Xiang Z, Cutler AJ, Brownlie RJ, Fairfax K, Lawlor KE, Severinson E, Walker EU, Manz RA, Tarlinton DM, Smith KG. Xiang Z, et al. Among authors: fairfax k. Nat Immunol. 2007 Apr;8(4):419-29. doi: 10.1038/ni1440. Epub 2007 Feb 18. Nat Immunol. 2007. PMID: 17322888
59 results