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Page 1
A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Clifton MC, Dranow DM, Leed A, Fulroth B, Fairman JW, Abendroth J, Atkins KA, Wallace E, Fan D, Xu G, Ni ZJ, Daniels D, Van Drie J, Wei G, Burgin AB, Golub TR, Hubbard BK, Serrano-Wu MH. Clifton MC, et al. Among authors: fairman jw. PLoS One. 2015 Apr 24;10(4):e0125010. doi: 10.1371/journal.pone.0125010. eCollection 2015. PLoS One. 2015. PMID: 25909780 Free PMC article.
Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).
Fang C, D'Souza B, Thompson CF, Clifton MC, Fairman JW, Fulroth B, Leed A, McCarren P, Wang L, Wang Y, Feau C, Kaushik VK, Palmer M, Wei G, Golub TR, Hubbard BK, Serrano-Wu MH. Fang C, et al. Among authors: fairman jw. ACS Med Chem Lett. 2014 Nov 11;5(12):1308-12. doi: 10.1021/ml500388q. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25516789 Free PMC article.
Combining functional and structural genomics to sample the essential Burkholderia structome.
Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC. Baugh L, et al. Among authors: fairman jw. PLoS One. 2013;8(1):e53851. doi: 10.1371/journal.pone.0053851. Epub 2013 Jan 31. PLoS One. 2013. PMID: 23382856 Free PMC article.
Increasing the structural coverage of tuberculosis drug targets.
Baugh L, Phan I, Begley DW, Clifton MC, Armour B, Dranow DM, Taylor BM, Muruthi MM, Abendroth J, Fairman JW, Fox D 3rd, Dieterich SH, Staker BL, Gardberg AS, Choi R, Hewitt SN, Napuli AJ, Myers J, Barrett LK, Zhang Y, Ferrell M, Mundt E, Thompkins K, Tran N, Lyons-Abbott S, Abramov A, Sekar A, Serbzhinskiy D, Lorimer D, Buchko GW, Stacy R, Stewart LJ, Edwards TE, Van Voorhis WC, Myler PJ. Baugh L, et al. Among authors: fairman jw. Tuberculosis (Edinb). 2015 Mar;95(2):142-8. doi: 10.1016/j.tube.2014.12.003. Epub 2014 Dec 19. Tuberculosis (Edinb). 2015. PMID: 25613812 Free PMC article.
Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Moen SO, Abendroth J, Fairman JW, Baydo RO, Bullen J, Kirkwood JL, Barnes SR, Raymond AC, Begley DW, Henkel G, McCormack K, Tam VC, Phan I, Staker BL, Stacy R, Myler PJ, Lorimer D, Edwards TE. Moen SO, et al. Among authors: fairman jw. Sci Rep. 2014 Aug 4;4:5944. doi: 10.1038/srep05944. Sci Rep. 2014. PMID: 25089892 Free PMC article.
Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.
Moen SO, Fairman JW, Barnes SR, Sullivan A, Nakazawa-Hewitt S, Van Voorhis WC, Staker BL, Lorimer DD, Myler PJ, Edwards TE. Moen SO, et al. Among authors: fairman jw. Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):609-14. doi: 10.1107/S2053230X15006883. Epub 2015 Apr 21. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25945716 Free PMC article.
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.
Phan IQ, Davies DR, Moretti NS, Shanmugam D, Cestari I, Anupama A, Fairman JW, Edwards TE, Stuart K, Schenkman S, Myler PJ. Phan IQ, et al. Among authors: fairman jw. Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):615-21. doi: 10.1107/S2053230X15004185. Epub 2015 May 7. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25961325 Free PMC article.
An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum.
Oliva Chávez AS, Fairman JW, Felsheim RF, Nelson CM, Herron MJ, Higgins L, Burkhardt NY, Oliver JD, Markowski TW, Kurtti TJ, Edwards TE, Munderloh UG. Oliva Chávez AS, et al. Among authors: fairman jw. PLoS Pathog. 2015 Nov 6;11(11):e1005248. doi: 10.1371/journal.ppat.1005248. eCollection 2015. PLoS Pathog. 2015. PMID: 26544981 Free PMC article.
19 results