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Page 1
BCL2L13 at endoplasmic reticulum-mitochondria contact sites regulates calcium homeostasis to maintain skeletal muscle function.
Grepper D, Tabasso C, Zanou N, Aguettaz AKF, Castro-Sepulveda M, Ziegler DV, Lagarrigue S, Arribat Y, Martinotti A, Ebrahimi A, Daraspe J, Fajas L, Amati F. Grepper D, et al. Among authors: fajas l. iScience. 2024 Jul 14;27(8):110510. doi: 10.1016/j.isci.2024.110510. eCollection 2024 Aug 16. iScience. 2024. PMID: 39175772 Free PMC article.
E2F transcription factor-1 modulates expression of glutamine metabolic genes in mouse embryonic fibroblasts and uterine sarcoma cells.
Huber K, Giralt A, Dreos R, Michenthaler H, Geller S, Barquissau V, Ziegler DV, Tavernari D, Gallart-Ayala H, Krajina K, Jonas K, Ciriello G, Ivanisevic J, Prokesch A, Pichler M, Fajas L. Huber K, et al. Among authors: fajas l. Biochim Biophys Acta Mol Cell Res. 2024 Jun;1871(5):119721. doi: 10.1016/j.bbamcr.2024.119721. Epub 2024 Apr 3. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 38580088 Free article.
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Martín J, Ortega S, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Among authors: fajas l. Mol Cell. 2024 Jun 20;84(12):2397. doi: 10.1016/j.molcel.2024.05.021. Epub 2024 May 31. Mol Cell. 2024. PMID: 38823385 No abstract available.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: fajas l. J Clin Invest. 2023 Mar 15;133(6):e170315. doi: 10.1172/JCI170315. J Clin Invest. 2023. PMID: 36919703 Free PMC article. No abstract available.
CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer.
Ziegler DV, Parashar K, Leal-Esteban L, López-Alcalá J, Castro W, Zanou N, Martinez-Carreres L, Huber K, Berney XP, Malagón MM, Roger C, Berger MA, Gouriou Y, Paone G, Gallart-Ayala H, Sflomos G, Ronchi C, Ivanisevic J, Brisken C, Rieusset J, Irving M, Fajas L. Ziegler DV, et al. Among authors: fajas l. Nat Commun. 2025 Jan 9;16(1):541. doi: 10.1038/s41467-024-55605-z. Nat Commun. 2025. PMID: 39788939 Free PMC article.
β-Cell-Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion.
Oger F, Bourouh C, Friano ME, Courty E, Rolland L, Gromada X, Moreno M, Carney C, Rabhi N, Durand E, Amanzougarene S, Berberian L, Derhourhi M, Blanc E, Hannou SA, Denechaud PD, Benfodda Z, Meffre P, Fajas L, Kerr-Conte J, Pattou F, Froguel P, Pourcet B, Bonnefond A, Collombat P, Annicotte JS. Oger F, et al. Among authors: fajas l. Diabetes. 2023 Aug 1;72(8):1112-1126. doi: 10.2337/db22-0604. Diabetes. 2023. PMID: 37216637
Oxidative stress-induced FAK activation contributes to uterine serous carcinoma aggressiveness.
Lopez-Mejia IC, Pijuan J, Navaridas R, Santacana M, Gatius S, Velasco A, Castellà G, Panosa A, Cabiscol E, Pinyol M, Coll L, Bonifaci N, Peña LP, Vidal A, Villanueva A, Gari E, Llobet-Navàs D, Fajas L, Matias-Guiu X, Yeramian A. Lopez-Mejia IC, et al. Among authors: fajas l. Mol Oncol. 2023 Jan;17(1):98-118. doi: 10.1002/1878-0261.13346. Epub 2022 Dec 7. Mol Oncol. 2023. PMID: 36409196 Free PMC article.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: fajas l. J Clin Invest. 2022 Jul 1;132(13):e162359. doi: 10.1172/JCI162359. J Clin Invest. 2022. PMID: 35775487 Free PMC article. No abstract available.
119 results