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Patterns of white matter hyperintensities associated with cognition in middle-aged cognitively healthy individuals.
Brugulat-Serrat A, Salvadó G, Sudre CH, Grau-Rivera O, Suárez-Calvet M, Falcon C, Sánchez-Benavides G, Gramunt N, Fauria K, Cardoso MJ, Barkhof F, Molinuevo JL, Gispert JD; ALFA Study. Brugulat-Serrat A, et al. Among authors: falcon c. Brain Imaging Behav. 2020 Oct;14(5):2012-2023. doi: 10.1007/s11682-019-00151-2. Brain Imaging Behav. 2020. PMID: 31278650 Free PMC article.
White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants.
Brugulat-Serrat A, Salvadó G, Operto G, Cacciaglia R, Sudre CH, Grau-Rivera O, Suárez-Calvet M, Falcon C, Sánchez-Benavides G, Gramunt N, Minguillon C, Fauria K, Barkhof F, Molinuevo JL, Gispert JD; ALFA Study. Brugulat-Serrat A, et al. Among authors: falcon c. Hum Brain Mapp. 2020 Apr 1;41(5):1309-1322. doi: 10.1002/hbm.24877. Epub 2019 Nov 28. Hum Brain Mapp. 2020. PMID: 31778002 Free PMC article.
Association of years to parent's sporadic onset and risk factors with neural integrity and Alzheimer biomarkers.
Arenaza-Urquijo EM, Salvadó G, Operto G, Minguillón C, Sánchez-Benavides G, Crous-Bou M, Grau-Rivera O, Sala-Vila A, Falcón C, Suárez-Calvet M, Zetterberg H, Blennow K, Gispert JD, Molinuevo JL; ALFA Study. Arenaza-Urquijo EM, et al. Among authors: falcon c. Neurology. 2020 Oct 13;95(15):e2065-e2074. doi: 10.1212/WNL.0000000000010527. Epub 2020 Jul 31. Neurology. 2020. PMID: 32737076 Free PMC article.
Nonlinear interaction between APOE ε4 allele load and age in the hippocampal surface of cognitively intact individuals.
Martí-Juan G, Sanroma-Guell G, Cacciaglia R, Falcon C, Operto G, Molinuevo JL, González Ballester MÁ, Gispert JD, Piella G; Alzheimer's Disease Neuroimaging Initiative; ALFA Study. Martí-Juan G, et al. Among authors: falcon c. Hum Brain Mapp. 2021 Jan;42(1):47-64. doi: 10.1002/hbm.25202. Epub 2020 Oct 5. Hum Brain Mapp. 2021. PMID: 33017488 Free PMC article.
Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer's continuum when only subtle changes in Aβ pathology are detected.
Suárez-Calvet M, Karikari TK, Ashton NJ, Lantero Rodríguez J, Milà-Alomà M, Gispert JD, Salvadó G, Minguillon C, Fauria K, Shekari M, Grau-Rivera O, Arenaza-Urquijo EM, Sala-Vila A, Sánchez-Benavides G, González-de-Echávarri JM, Kollmorgen G, Stoops E, Vanmechelen E, Zetterberg H, Blennow K, Molinuevo JL; ALFA Study. Suárez-Calvet M, et al. EMBO Mol Med. 2020 Dec 7;12(12):e12921. doi: 10.15252/emmm.202012921. Epub 2020 Nov 10. EMBO Mol Med. 2020. PMID: 33169916 Free PMC article.
Association of weight change with cerebrospinal fluid biomarkers and amyloid positron emission tomography in preclinical Alzheimer's disease.
Grau-Rivera O, Navalpotro-Gomez I, Sánchez-Benavides G, Suárez-Calvet M, Milà-Alomà M, Arenaza-Urquijo EM, Salvadó G, Sala-Vila A, Shekari M, González-de-Echávarri JM, Minguillón C, Niñerola-Baizán A, Perissinotti A, Simon M, Kollmorgen G, Zetterberg H, Blennow K, Gispert JD, Molinuevo JL; ALFA Study. Grau-Rivera O, et al. Alzheimers Res Ther. 2021 Feb 17;13(1):46. doi: 10.1186/s13195-021-00781-z. Alzheimers Res Ther. 2021. PMID: 33597012 Free PMC article.
Cognitively unimpaired individuals with a low burden of Aβ pathology have a distinct CSF biomarker profile.
Milà-Alomà M, Shekari M, Salvadó G, Gispert JD, Arenaza-Urquijo EM, Operto G, Falcon C, Vilor-Tejedor N, Grau-Rivera O, Sala-Vila A, Sánchez-Benavides G, González-de-Echávarri JM, Minguillon C, Fauria K, Niñerola-Baizán A, Perissinotti A, Simon M, Kollmorgen G, Zetterberg H, Blennow K, Suárez-Calvet M, Molinuevo JL; ALFA study. Milà-Alomà M, et al. Among authors: falcon c. Alzheimers Res Ther. 2021 Jul 27;13(1):134. doi: 10.1186/s13195-021-00863-y. Alzheimers Res Ther. 2021. PMID: 34315519 Free PMC article. Clinical Trial.
278 results