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The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.
Bhattacharyya RP, Reményi A, Good MC, Bashor CJ, Falick AM, Lim WA. Bhattacharyya RP, et al. Among authors: falick am. Science. 2006 Feb 10;311(5762):822-6. doi: 10.1126/science.1120941. Epub 2006 Jan 19. Science. 2006. PMID: 16424299
Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.
Lombana TN, Echols N, Good MC, Thomsen ND, Ng HL, Greenstein AE, Falick AM, King DS, Alber T. Lombana TN, et al. Among authors: falick am. Structure. 2010 Dec 8;18(12):1667-77. doi: 10.1016/j.str.2010.09.019. Structure. 2010. PMID: 21134645 Free PMC article.
A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria.
Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. Gee CL, et al. Among authors: falick am. Sci Signal. 2012 Jan 24;5(208):ra7. doi: 10.1126/scisignal.2002525. Sci Signal. 2012. PMID: 22275220 Free PMC article.
Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases.
Young TA, Delagoutte B, Endrizzi JA, Falick AM, Alber T. Young TA, et al. Among authors: falick am. Nat Struct Biol. 2003 Mar;10(3):168-74. doi: 10.1038/nsb897. Nat Struct Biol. 2003. PMID: 12548283
High yield bacterial expression of active c-Abl and c-Src tyrosine kinases.
Seeliger MA, Young M, Henderson MN, Pellicena P, King DS, Falick AM, Kuriyan J. Seeliger MA, et al. Among authors: falick am. Protein Sci. 2005 Dec;14(12):3135-9. doi: 10.1110/ps.051750905. Epub 2005 Oct 31. Protein Sci. 2005. PMID: 16260764 Free PMC article.
Activation of a phytopathogenic bacterial effector protein by a eukaryotic cyclophilin.
Coaker G, Falick A, Staskawicz B. Coaker G, et al. Among authors: falick a. Science. 2005 Apr 22;308(5721):548-50. doi: 10.1126/science.1108633. Epub 2005 Mar 3. Science. 2005. PMID: 15746386
Mapping a membrane-associated conformation of colicin Ia.
Mel SF, Falick AM, Burlingame AL, Stroud RM. Mel SF, et al. Among authors: falick am. Biochemistry. 1993 Sep 14;32(36):9473-9. doi: 10.1021/bi00087a027. Biochemistry. 1993. PMID: 7690252
Identification of protein-protein interfaces by decreased amide proton solvent accessibility.
Mandell JG, Falick AM, Komives EA. Mandell JG, et al. Among authors: falick am. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14705-10. doi: 10.1073/pnas.95.25.14705. Proc Natl Acad Sci U S A. 1998. PMID: 9843953 Free PMC article.
Identification of the heme-modified peptides from cumene hydroperoxide-inactivated cytochrome P450 3A4.
He K, Bornheim LM, Falick AM, Maltby D, Yin H, Correia MA. He K, et al. Among authors: falick am. Biochemistry. 1998 Dec 15;37(50):17448-57. doi: 10.1021/bi9808464. Biochemistry. 1998. PMID: 9860860
Probing the binding region of the single-stranded DNA-binding domain of rat DNA polymerase beta using nanosecond-pulse laser-induced cross-linking and mass spectrometry.
Connor DA, Falick AM, Young MC, Shetlar MD. Connor DA, et al. Among authors: falick am. Photochem Photobiol. 1998 Sep;68(3):299-308. Photochem Photobiol. 1998. PMID: 9747586
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