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Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L, La Starza R, Diverio D, Colombo E, Santucci A, Bigerna B, Pacini R, Pucciarini A, Liso A, Vignetti M, Fazi P, Meani N, Pettirossi V, Saglio G, Mandelli F, Lo-Coco F, Pelicci PG, Martelli MF; GIMEMA Acute Leukemia Working Party. Falini B, et al. N Engl J Med. 2005 Jan 20;352(3):254-66. doi: 10.1056/NEJMoa041974. N Engl J Med. 2005. PMID: 15659725
Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance.
Alcalay M, Tiacci E, Bergomas R, Bigerna B, Venturini E, Minardi SP, Meani N, Diverio D, Bernard L, Tizzoni L, Volorio S, Luzi L, Colombo E, Lo Coco F, Mecucci C, Falini B, Pelicci PG. Alcalay M, et al. Among authors: falini b. Blood. 2005 Aug 1;106(3):899-902. doi: 10.1182/blood-2005-02-0560. Epub 2005 Apr 14. Blood. 2005. PMID: 15831697
Nucleophosmin is required for DNA integrity and p19Arf protein stability.
Colombo E, Bonetti P, Lazzerini Denchi E, Martinelli P, Zamponi R, Marine JC, Helin K, Falini B, Pelicci PG. Colombo E, et al. Among authors: falini b. Mol Cell Biol. 2005 Oct;25(20):8874-86. doi: 10.1128/MCB.25.20.8874-8886.2005. Mol Cell Biol. 2005. PMID: 16199867 Free PMC article.
415 results