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Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1.
Monack DM, Detweiler CS, Falkow S. Monack DM, et al. Cell Microbiol. 2001 Dec;3(12):825-37. doi: 10.1046/j.1462-5822.2001.00162.x. Cell Microbiol. 2001. PMID: 11736994
The delayed cell death has previously been shown with S. typhimurium to be dependent on SPI2-encoded genes and ompR. Using caspase-1(-/-) bone marrow-derived macrophages and isogenic S. typhimurium mutant strains, we show that a large portion of the delayed, SPI2-de …
The delayed cell death has previously been shown with S. typhimurium to be dependent on SPI2-encoded genes and ompR. Using caspase-1( …
Sequence anomalies in the Cag7 gene of the Helicobacter pylori pathogenicity island.
Liu G, McDaniel TK, Falkow S, Karlin S. Liu G, et al. Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7011-6. doi: 10.1073/pnas.96.12.7011. Proc Natl Acad Sci U S A. 1999. PMID: 10359830 Free PMC article.
Induction of host signal transduction pathways by Helicobacter pylori.
Segal ED, Lange C, Covacci A, Tompkins LS, Falkow S. Segal ED, et al. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7595-9. doi: 10.1073/pnas.94.14.7595. Proc Natl Acad Sci U S A. 1997. PMID: 9207137 Free PMC article.
The fortunate professor.
Falkow S. Falkow S. Annu Rev Microbiol. 2008;62:1-18. doi: 10.1146/annurev.micro.62.081307.162931. Annu Rev Microbiol. 2008. PMID: 18345978
Common themes in microbial pathogenicity revisited.
Finlay BB, Falkow S. Finlay BB, et al. Microbiol Mol Biol Rev. 1997 Jun;61(2):136-69. Microbiol Mol Biol Rev. 1997. PMID: 9184008 Free PMC article. Review.
Salmonella as an intracellular parasite.
Finlay BB, Falkow S. Finlay BB, et al. Mol Microbiol. 1989 Dec;3(12):1833-41. doi: 10.1111/j.1365-2958.1989.tb00170.x. Mol Microbiol. 1989. PMID: 2695752 Review.
Characterization of a Salmonella choleraesuis mutant that cannot multiply within epithelial cells.
Finlay BB, Chatfield S, Leung KY, Dougan G, Falkow S. Finlay BB, et al. Can J Microbiol. 1991 Jul;37(7):568-72. doi: 10.1139/m91-095. Can J Microbiol. 1991. PMID: 1913359
These results suggest that the ability to multiply within eukaryotic cells may contribute to S. choleraesuis virulence....
These results suggest that the ability to multiply within eukaryotic cells may contribute to S. choleraesuis virulence....
Salmonellosis: host immune responses and bacterial virulence determinants.
Jones BD, Falkow S. Jones BD, et al. Annu Rev Immunol. 1996;14:533-61. doi: 10.1146/annurev.immunol.14.1.533. Annu Rev Immunol. 1996. PMID: 8717524 Review.
These proteins are used by the bacteria to penetrate the intestinal mucosa by invading and destroying specialized epithelial M cells of the Peyer's patches. ...
These proteins are used by the bacteria to penetrate the intestinal mucosa by invading and destroying specialized epithelial M cells of the …
Host restriction phenotypes of Salmonella typhi and Salmonella gallinarum.
Pascopella L, Raupach B, Ghori N, Monack D, Falkow S, Small PL. Pascopella L, et al. Infect Immun. 1995 Nov;63(11):4329-35. doi: 10.1128/IAI.63.11.4329-4335.1995. Infect Immun. 1995. PMID: 7591067 Free PMC article.
But, unlike S. typhimurium, S. typhi does not destroy the epithelium and is cleared from the Peyer's patches soon after M-cell entry. S. gallinarum appears to be incapable of entering the murine Peyer's patch epithelium. Our in vitro evidence su …
But, unlike S. typhimurium, S. typhi does not destroy the epithelium and is cleared from the Peyer's patches soon after …
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