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Vinyl sulfone analogs of lysophosphatidylcholine irreversibly inhibit autotaxin and prevent angiogenesis in melanoma.
Bioorg Med Chem. 2015 Sep 1;23(17):5999-6013. doi: 10.1016/j.bmc.2015.06.054. Epub 2015 Jul 2.
Bioorg Med Chem. 2015.
PMID: 26190462
Free PMC article.
Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model.
Altman MK, Nguyen DT, Patel SB, Fambrough JM, Beedle AM, Hardman WJ, Murph MM.
Altman MK, et al. Among authors: fambrough jm.
Biochem Res Int. 2012;2012:518437. doi: 10.1155/2012/518437. Epub 2012 Jun 25.
Biochem Res Int. 2012.
PMID: 22792465
Free PMC article.
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Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.
Altman MK, Alshamrani AA, Jia W, Nguyen HT, Fambrough JM, Tran SK, Patel MB, Hoseinzadeh P, Beedle AM, Murph MM.
Altman MK, et al. Among authors: fambrough jm.
Cancer Lett. 2015 Dec 1;369(1):175-83. doi: 10.1016/j.canlet.2015.08.012. Epub 2015 Aug 28.
Cancer Lett. 2015.
PMID: 26319900
Free PMC article.
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