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Page 1
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation.
Kelley N, Jeltema D, Duan Y, He Y. Kelley N, et al. Int J Mol Sci. 2019 Jul 6;20(13):3328. doi: 10.3390/ijms20133328. Int J Mol Sci. 2019. PMID: 31284572 Free PMC article. Review.
However, the aberrant activation of the NLRP3 inflammasome has been linked with several inflammatory disorders, which include cryopyrin-associated periodic syndromes, Alzheimer's disease, diabetes, and atherosclerosis. ...
However, the aberrant activation of the NLRP3 inflammasome has been linked with several inflammatory disorders, which include cryopyrin
Classification criteria for autoinflammatory recurrent fevers.
Gattorno M, Hofer M, Federici S, Vanoni F, Bovis F, Aksentijevich I, Anton J, Arostegui JI, Barron K, Ben-Cherit E, Brogan PA, Cantarini L, Ceccherini I, De Benedetti F, Dedeoglu F, Demirkaya E, Frenkel J, Goldbach-Mansky R, Gul A, Hentgen V, Hoffman H, Kallinich T, Kone-Paut I, Kuemmerle-Deschner J, Lachmann HJ, Laxer RM, Livneh A, Obici L, Ozen S, Rowczenio D, Russo R, Shinar Y, Simon A, Toplak N, Touitou I, Uziel Y, van Gijn M, Foell D, Garassino C, Kastner D, Martini A, Sormani MP, Ruperto N; Eurofever Registry and the Paediatric Rheumatology International Trials Organisation (PRINTO). Gattorno M, et al. Ann Rheum Dis. 2019 Aug;78(8):1025-1032. doi: 10.1136/annrheumdis-2019-215048. Epub 2019 Apr 24. Ann Rheum Dis. 2019. PMID: 31018962 Review.
BACKGROUND: Different diagnostic and classification criteria are available for hereditary recurrent fevers (HRF)-familial Mediterranean fever (FMF), tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS), mevalonate kinase deficiency (MKD) and cryopy
BACKGROUND: Different diagnostic and classification criteria are available for hereditary recurrent fevers (HRF)-familial Mediterranean feve …
CAPS and NLRP3.
Booshehri LM, Hoffman HM. Booshehri LM, et al. J Clin Immunol. 2019 Apr;39(3):277-286. doi: 10.1007/s10875-019-00638-z. Epub 2019 May 10. J Clin Immunol. 2019. PMID: 31077002 Free PMC article. Review.
Cryopyrin-associated periodic syndrome (CAPS) is a rare inherited autoinflammatory disorder characterized by systemic, cutaneous, musculoskeletal, and central nervous system inflammation. ...
Cryopyrin-associated periodic syndrome (CAPS) is a rare inherited autoinflammatory disorder characterized by systemic,
Periodic fever syndromes.
Lachmann HJ. Lachmann HJ. Best Pract Res Clin Rheumatol. 2017 Aug;31(4):596-609. doi: 10.1016/j.berh.2017.12.001. Epub 2018 Jan 11. Best Pract Res Clin Rheumatol. 2017. PMID: 29773275 Review.
Periodic fever syndromes are autoinflammatory diseases. The majority present in infancy or childhood and are characterised by recurrent episodes of fever and systemic inflammation that occur in the absence of autoantibody production or identifiable infection. ...Wit
Periodic fever syndromes are autoinflammatory diseases. The majority present in infancy or childhood and are characterised by
Mitochondria in innate immune signaling.
Banoth B, Cassel SL. Banoth B, et al. Transl Res. 2018 Dec;202:52-68. doi: 10.1016/j.trsl.2018.07.014. Epub 2018 Aug 7. Transl Res. 2018. PMID: 30165038 Free PMC article. Review.
Neutrophilic urticarial dermatosis: A review.
Gusdorf L, Lipsker D. Gusdorf L, et al. Ann Dermatol Venereol. 2018 Dec;145(12):735-740. doi: 10.1016/j.annder.2018.06.010. Epub 2018 Sep 14. Ann Dermatol Venereol. 2018. PMID: 30224079 Review.
The most commonly associated diseases are adult-onset Still's disease, Schnitzler syndrome, lupus erythematosus and cryopyrin-associated periodic syndromes. Treatment of NUD depends on the clinical context. ...
The most commonly associated diseases are adult-onset Still's disease, Schnitzler syndrome, lupus erythematosus and cryopyrin-asso
Systemic autoinflammatory diseases: Clinical state of the art.
Georgin-Lavialle S, Ducharme-Benard S, Sarrabay G, Savey L, Grateau G, Hentgen V. Georgin-Lavialle S, et al. Best Pract Res Clin Rheumatol. 2020 Aug;34(4):101529. doi: 10.1016/j.berh.2020.101529. Epub 2020 Jun 13. Best Pract Res Clin Rheumatol. 2020. PMID: 32546426 Free article. Review.
The four historical monogenic diseases are familial Mediterranean fever (associated with MEFV mutations), cryopyrinopathies (NLRP3 mutations), tumor necrosis factor receptor-associated periodic syndrome (TNFRSF1A mutations), and mevalonate kinase deficiency (MVK mutations) …
The four historical monogenic diseases are familial Mediterranean fever (associated with MEFV mutations), cryopyrinopathies (NLRP3 mutations …
Mimickers of Urticaria: Urticarial Vasculitis and Autoinflammatory Diseases.
Davis MDP, van der Hilst JCH. Davis MDP, et al. J Allergy Clin Immunol Pract. 2018 Jul-Aug;6(4):1162-1170. doi: 10.1016/j.jaip.2018.05.006. Epub 2018 Jun 2. J Allergy Clin Immunol Pract. 2018. PMID: 29871797 Review.
This review will specifically address urticarial vasculitis and autoinflammatory syndromes. These entities represent contrasting examples of urticarial-like lesions resulting from either an adaptive immune complex-mediated mechanism (urticarial vasculitis) or an innate imm …
This review will specifically address urticarial vasculitis and autoinflammatory syndromes. These entities represent contrasting exam …
The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors.
Zhan X, Li Q, Xu G, Xiao X, Bai Z. Zhan X, et al. Front Immunol. 2023 Jan 18;13:1109938. doi: 10.3389/fimmu.2022.1109938. eCollection 2022. Front Immunol. 2023. PMID: 36741414 Free PMC article. Review.
Aberrant NLRP3 inflammasome activation is linked with the pathogenesis of multiple inflammatory diseases, such as cryopyrin-associated periodic syndromes, type 2 diabetes, non-alcoholic steatohepatitis, gout, and neurodegenerative diseases. ...
Aberrant NLRP3 inflammasome activation is linked with the pathogenesis of multiple inflammatory diseases, such as cryopyrin-associ
Urticarial vasculitis: Clinical and laboratory findings with a particular emphasis on differential diagnosis.
Marzano AV, Maronese CA, Genovese G, Ferrucci S, Moltrasio C, Asero R, Cugno M. Marzano AV, et al. J Allergy Clin Immunol. 2022 Apr;149(4):1137-1149. doi: 10.1016/j.jaci.2022.02.007. J Allergy Clin Immunol. 2022. PMID: 35396080 Review.
A focus on its main differential diagnoses is provided, that is, chronic spontaneous urticaria, bullous pemphigoid, IgA (Henoch-Schonlein purpura) and IgM/IgG immune complex vasculitis, lupus erythematous tumidus, Wells syndrome, erythema multiforme, cutaneous mastocytosis, cr
A focus on its main differential diagnoses is provided, that is, chronic spontaneous urticaria, bullous pemphigoid, IgA (Henoch-Schonlein pu …
217 results