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Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma.
Tschaharganeh DF, Chen X, Latzko P, Malz M, Gaida MM, Felix K, Ladu S, Singer S, Pinna F, Gretz N, Sticht C, Tomasi ML, Delogu S, Evert M, Fan B, Ribback S, Jiang L, Brozzetti S, Bergmann F, Dombrowski F, Schirmacher P, Calvisi DF, Breuhahn K. Tschaharganeh DF, et al. Among authors: fan b. Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16. Gastroenterology. 2013. PMID: 23419361 Free PMC article.
Cholangiocarcinomas can originate from hepatocytes in mice.
Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, Gores GJ, Dombrowski F, Evert M, Chen X, Willenbring H. Fan B, et al. J Clin Invest. 2012 Aug;122(8):2911-5. doi: 10.1172/JCI63212. Epub 2012 Jul 17. J Clin Invest. 2012. PMID: 22797301 Free PMC article.
Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.
Tao J, Calvisi DF, Ranganathan S, Cigliano A, Zhou L, Singh S, Jiang L, Fan B, Terracciano L, Armeanu-Ebinger S, Ribback S, Dombrowski F, Evert M, Chen X, Monga SPS. Tao J, et al. Among authors: fan b. Gastroenterology. 2014 Sep;147(3):690-701. doi: 10.1053/j.gastro.2014.05.004. Epub 2014 May 14. Gastroenterology. 2014. PMID: 24837480 Free PMC article.
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.
Zhang S, Song X, Cao D, Xu Z, Fan B, Che L, Hu J, Chen B, Dong M, Pilo MG, Cigliano A, Evert K, Ribback S, Dombrowski F, Pascale RM, Cossu A, Vidili G, Porcu A, Simile MM, Pes GM, Giannelli G, Gordan J, Wei L, Evert M, Cong W, Calvisi DF, Chen X. Zhang S, et al. Among authors: fan b. J Hepatol. 2017 Dec;67(6):1194-1203. doi: 10.1016/j.jhep.2017.07.006. Epub 2017 Jul 19. J Hepatol. 2017. PMID: 28733220 Free PMC article.
Hippo Cascade Controls Lineage Commitment of Liver Tumors in Mice and Humans.
Zhang S, Wang J, Wang H, Fan L, Fan B, Zeng B, Tao J, Li X, Che L, Cigliano A, Ribback S, Dombrowski F, Chen B, Cong W, Wei L, Calvisi DF, Chen X. Zhang S, et al. Among authors: fan l, fan b. Am J Pathol. 2018 Apr;188(4):995-1006. doi: 10.1016/j.ajpath.2017.12.017. Epub 2018 Jan 31. Am J Pathol. 2018. PMID: 29378174 Free PMC article.
YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice.
Lu X, Peng B, Chen G, Pes MG, Ribback S, Ament C, Xu H, Pal R, Rodrigues PM, Banales JM, Evert M, Calvisi DF, Chen X, Fan B, Wang J. Lu X, et al. Among authors: fan b. Am J Pathol. 2021 Sep;191(9):1651-1667. doi: 10.1016/j.ajpath.2021.05.017. Epub 2021 Jun 12. Am J Pathol. 2021. PMID: 34129844 Free PMC article.
2,924 results