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9,657 results
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Interplay of transporters and enzymes in drug and metabolite processing.
Pang KS, Maeng HJ, Fan J. Pang KS, et al. Among authors: fan j. Mol Pharm. 2009 Nov-Dec;6(6):1734-55. doi: 10.1021/mp900258z. Mol Pharm. 2009. PMID: 19891494 Review.
Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo.
Yang QJ, Fan J, Chen S, Liu L, Sun H, Pang KS. Yang QJ, et al. Among authors: fan j. Drug Metab Dispos. 2016 Jul;44(7):1123-38. doi: 10.1124/dmd.116.069542. Epub 2016 Apr 20. Drug Metab Dispos. 2016. PMID: 27098743
PBPK modeling of intestinal and liver enzymes and transporters in drug absorption and sequential metabolism.
Fan J, Chen S, Chow EC, Pang KS. Fan J, et al. Curr Drug Metab. 2010 Nov;11(9):743-61. doi: 10.2174/138920010794328931. Curr Drug Metab. 2010. PMID: 21189137 Review.
Interplay of transporters and enzymes in the Caco-2 cell monolayer: I. effect of altered apical secretion.
Fan J, Maeng HJ, Pang KS. Fan J, et al. Biopharm Drug Dispos. 2010 May;31(4):215-27. doi: 10.1002/bdd.704. Biopharm Drug Dispos. 2010. PMID: 20437461
Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1alpha,25-dihydroxyvitamin D3 and vitamin D analogs, in the Caco-2 cell monolayer.
Fan J, Liu S, Du Y, Morrison J, Shipman R, Pang KS. Fan J, et al. J Pharmacol Exp Ther. 2009 Aug;330(2):389-402. doi: 10.1124/jpet.108.149815. Epub 2009 May 4. J Pharmacol Exp Ther. 2009. PMID: 19414624
Vitamin D receptor activation induces P-glycoprotein and increases brain efflux of quinidine: an intracerebral microdialysis study in conscious rats.
Durk MR, Fan J, Sun H, Yang Y, Pang H, Pang KS, de Lannoy IA. Durk MR, et al. Among authors: fan j. Pharm Res. 2015 Mar;32(3):1128-40. doi: 10.1007/s11095-014-1524-y. Epub 2014 Oct 16. Pharm Res. 2015. PMID: 25319098
Pharmacokinetics.
Fan J, de Lannoy IA. Fan J, et al. Biochem Pharmacol. 2014 Jan 1;87(1):93-120. doi: 10.1016/j.bcp.2013.09.007. Epub 2013 Sep 17. Biochem Pharmacol. 2014. PMID: 24055064 Review.
Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.
Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS. Chow EC, et al. Among authors: fan j. Gastroenterology. 2014 Apr;146(4):1048-59. doi: 10.1053/j.gastro.2013.12.027. Epub 2013 Dec 21. Gastroenterology. 2014. PMID: 24365583
Cloning and promoter activity of rat Smad1 5'-flanking region in rat hepatic stellate cells.
Sun Y, Fan J, Shen H, Li P, Cattini P, Gong Y. Sun Y, et al. Among authors: fan j. Mol Cell Biochem. 2007 Oct;304(1-2):227-34. doi: 10.1007/s11010-007-9504-8. Epub 2007 May 26. Mol Cell Biochem. 2007. PMID: 17530186
Bone morphogenetic protein 4 mediates bile duct ligation induced liver fibrosis through activation of Smad1 and ERK1/2 in rat hepatic stellate cells.
Fan J, Shen H, Sun Y, Li P, Burczynski F, Namaka M, Gong Y. Fan J, et al. J Cell Physiol. 2006 May;207(2):499-505. doi: 10.1002/jcp.20593. J Cell Physiol. 2006. PMID: 16447265
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