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MYCN amplification and ATRX mutations are incompatible in neuroblastoma.
Zeineldin M, Federico S, Chen X, Fan Y, Xu B, Stewart E, Zhou X, Jeon J, Griffiths L, Nguyen R, Norrie J, Easton J, Mulder H, Yergeau D, Liu Y, Wu J, Van Ryn C, Naranjo A, Hogarty MD, Kamiński MM, Valentine M, Pruett-Miller SM, Pappo A, Zhang J, Clay MR, Bahrami A, Vogel P, Lee S, Shelat A, Sarthy JF, Meers MP, George RE, Mardis ER, Wilson RK, Henikoff S, Downing JR, Dyer MA. Zeineldin M, et al. Among authors: fan y. Nat Commun. 2020 Feb 14;11(1):913. doi: 10.1038/s41467-020-14682-6. Nat Commun. 2020. PMID: 32060267 Free PMC article.
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells.
Diouf B, Cheng Q, Krynetskaia NF, Yang W, Cheok M, Pei D, Fan Y, Cheng C, Krynetskiy EY, Geng H, Chen S, Thierfelder WE, Mullighan CG, Downing JR, Hsieh P, Pui CH, Relling MV, Evans WE. Diouf B, et al. Among authors: fan y. Nat Med. 2011 Sep 25;17(10):1298-303. doi: 10.1038/nm.2430. Nat Med. 2011. PMID: 21946537 Free PMC article.
Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.
Hiler D, Chen X, Hazen J, Kupriyanov S, Carroll PA, Qu C, Xu B, Johnson D, Griffiths L, Frase S, Rodriguez AR, Martin G, Zhang J, Jeon J, Fan Y, Finkelstein D, Eisenman RN, Baldwin K, Dyer MA. Hiler D, et al. Among authors: fan y. Cell Stem Cell. 2015 Jul 2;17(1):101-15. doi: 10.1016/j.stem.2015.05.015. Cell Stem Cell. 2015. PMID: 26140606 Free PMC article.
Evaluation of artemisinins for the treatment of acute myeloid leukemia.
Drenberg CD, Buaboonnam J, Orwick SJ, Hu S, Li L, Fan Y, Shelat AA, Guy RK, Rubnitz J, Baker SD. Drenberg CD, et al. Among authors: fan y. Cancer Chemother Pharmacol. 2016 Jun;77(6):1231-43. doi: 10.1007/s00280-016-3038-2. Epub 2016 Apr 28. Cancer Chemother Pharmacol. 2016. PMID: 27125973 Free PMC article.
An unexpected protein interaction promotes drug resistance in leukemia.
Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, Gruber TA, Centonze VE, Naren AP, Chen T, Schuetz JD. Pitre A, et al. Among authors: fan y. Nat Commun. 2017 Nov 16;8(1):1547. doi: 10.1038/s41467-017-01678-y. Nat Commun. 2017. PMID: 29146910 Free PMC article.
Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.
Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, Gordon B, Dapper J, Blankenship K, Yang Y, Li Y, Shaw TI, Cho JH, Wang X, Xu B, Gupta P, Fan Y, Liu Y, Rusch M, Griffiths L, Jeon J, Freeman BB 3rd, Clay MR, Pappo A, Easton J, Shurtleff S, Shelat A, Zhou X, Boggs K, Mulder H, Yergeau D, Bahrami A, Mardis ER, Wilson RK, Zhang J, Peng J, Downing JR, Dyer MA; St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project. Stewart E, et al. Among authors: fan y. Cancer Cell. 2018 Sep 10;34(3):411-426.e19. doi: 10.1016/j.ccell.2018.07.012. Epub 2018 Aug 23. Cancer Cell. 2018. PMID: 30146332 Free PMC article.
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