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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1995 5
1996 21
1997 24
1998 55
1999 60
2000 48
2001 62
2002 60
2003 49
2004 61
2005 54
2006 63
2007 67
2008 58
2009 49
2010 69
2011 59
2012 53
2013 50
2014 69
2015 68
2016 89
2017 67
2018 66
2019 67
2020 64
2021 78
2022 50
2023 58
2024 16

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1,547 results

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Page 1
Effect of BRCA germline mutations on breast cancer prognosis: A systematic review and meta-analysis.
Baretta Z, Mocellin S, Goldin E, Olopade OI, Huo D. Baretta Z, et al. Medicine (Baltimore). 2016 Oct;95(40):e4975. doi: 10.1097/MD.0000000000004975. Medicine (Baltimore). 2016. PMID: 27749552 Free PMC article. Review.
These studies involved 105,220 breast cancer patients, whose 3588 (3.4%) were BRCA mutations carriers. The associations between BRCA genes mutational status and overall survival (OS), breast cancer-specific survival (BCSS), recurrence-free survival (RFS), and distant metas …
These studies involved 105,220 breast cancer patients, whose 3588 (3.4%) were BRCA mutations carriers. The associations between BRCA gene
Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage.
Yoshida K, Miki Y. Yoshida K, et al. Cancer Sci. 2004 Nov;95(11):866-71. doi: 10.1111/j.1349-7006.2004.tb02195.x. Cancer Sci. 2004. PMID: 15546503 Free article. Review.
BRCA1 (BReast-CAncer susceptibility gene 1) and BRCA2 are tumor suppressor genes, the mutant phenotypes of which predispose to breast and ovarian cancers. Intensive research has shown that BRCA proteins are involved in a multitude of pivotal cellular processes. In p …
BRCA1 (BReast-CAncer susceptibility gene 1) and BRCA2 are tumor suppressor genes, the mutant phenotypes of which predispose to …
Breast cancer genes: beyond BRCA1 and BRCA2.
Filippini SE, Vega A. Filippini SE, et al. Front Biosci (Landmark Ed). 2013 Jun 1;18(4):1358-72. doi: 10.2741/4185. Front Biosci (Landmark Ed). 2013. PMID: 23747889 Free article. Review.
Familial breast cancer (about 30 percent of patients), often seen in families with a high incidence of BC, has been associated with a number of high-, moderate-, and low-penetrance susceptibility genes. Family linkage studies have identified high-penetrance genes, B …
Familial breast cancer (about 30 percent of patients), often seen in families with a high incidence of BC, has been associated with a number …
Breast cancer prevention in high-risk women.
Thorat MA, Balasubramanian R. Thorat MA, et al. Best Pract Res Clin Obstet Gynaecol. 2020 May;65:18-31. doi: 10.1016/j.bpobgyn.2019.11.006. Epub 2019 Nov 21. Best Pract Res Clin Obstet Gynaecol. 2020. PMID: 31862315 Review.
Women at high risk of developing breast cancer are a heterogeneous group of women including those with and without high-risk germline mutation/s. ...Bilateral risk-reducing salpingo-oophorectomy may also reduce risk in premenopausal BRCA2 carriers. Further research …
Women at high risk of developing breast cancer are a heterogeneous group of women including those with and without high-risk germline …
BRCA2 gene mutation in cancer.
Xie C, Luo J, He Y, Jiang L, Zhong L, Shi Y. Xie C, et al. Medicine (Baltimore). 2022 Nov 11;101(45):e31705. doi: 10.1097/MD.0000000000031705. Medicine (Baltimore). 2022. PMID: 36397405 Free PMC article. Review.
Breast cancer susceptibility gene 2 (BRCA2) is the main gene associated with hereditary breast cancers. ...In this review, we discuss the biological functions of BRCA2 and the role of BRCA2 mutations in tumor progression and therapy....
Breast cancer susceptibility gene 2 (BRCA2) is the main gene associated with hereditary breast cancers. ...In this review, we discuss …
Breast Cancer in Men.
Giordano SH. Giordano SH. N Engl J Med. 2018 Jun 14;378(24):2311-2320. doi: 10.1056/NEJMra1707939. N Engl J Med. 2018. PMID: 29897847 Review. No abstract available.
PARP Inhibitors and Prostate Cancer: To Infinity and Beyond BRCA.
Risdon EN, Chau CH, Price DK, Sartor O, Figg WD. Risdon EN, et al. Oncologist. 2021 Jan;26(1):e115-e129. doi: 10.1634/theoncologist.2020-0697. Epub 2020 Sep 8. Oncologist. 2021. PMID: 32790034 Free PMC article. Review.
The benefits of PARP inhibition have been well characterized in patients who have BRCA1 and BRCA2 mutations in several forms of cancer. BRCA1 and BRCA2 occupy key roles in DNA damage repair, which is comprised of several different pathways with numerous participants …
The benefits of PARP inhibition have been well characterized in patients who have BRCA1 and BRCA2 mutations in several forms of cance …
Functions of Breast Cancer Predisposition Genes: Implications for Clinical Management.
Yoshimura A, Imoto I, Iwata H. Yoshimura A, et al. Int J Mol Sci. 2022 Jul 5;23(13):7481. doi: 10.3390/ijms23137481. Int J Mol Sci. 2022. PMID: 35806485 Free PMC article. Review.
Approximately 5-10% of all breast cancer (BC) cases are caused by germline pathogenic variants (GPVs) in various cancer predisposition genes (CPGs). The most common contributors to hereditary BC are BRCA1 and BRCA2, which are associated with hereditary breast and ov …
Approximately 5-10% of all breast cancer (BC) cases are caused by germline pathogenic variants (GPVs) in various cancer predisposition ge
BRCA Genes and Related Cancers: A Meta-Analysis from Epidemiological Cohort Studies.
Lee YC, Lee YL, Li CY. Lee YC, et al. Medicina (Kaunas). 2021 Aug 30;57(9):905. doi: 10.3390/medicina57090905. Medicina (Kaunas). 2021. PMID: 34577828 Free PMC article. Review.
Background and Objectives:BRCA1 and BRCA2 are genes located in different chromosomes that are disproportionately associated with hereditary breast and ovarian cancer syndrome. ...BRCA mutation did not increase brain cancer; colorectal cancer; prostate, bladder and k …
Background and Objectives:BRCA1 and BRCA2 are genes located in different chromosomes that are disproportionately associated wi …
1,547 results