Fang Y - Search Results

1

Activation of mTOR signaling by novel fluoromethylene phosphonate analogues of phosphatidic acid.

Xu Y, Fang Y, Chen J, Prestwich GD. Xu Y, et al. Among authors: fang y. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1461-4. doi: 10.1016/j.bmcl.2004.01.020. Bioorg Med Chem Lett. 2004. PMID: 15006382

2

A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.

Chen J, Fang Y. Chen J, et al. Among authors: fang y. Biochem Pharmacol. 2002 Oct 1;64(7):1071-7. doi: 10.1016/s0006-2952(02)01263-7. Biochem Pharmacol. 2002. PMID: 12234610 Review.

3

Phosphatidic acid-mediated mitogenic activation of mTOR signaling.

Fang Y, Vilella-Bach M, Bachmann R, Flanigan A, Chen J. Fang Y, et al. Science. 2001 Nov 30;294(5548):1942-5. doi: 10.1126/science.1066015. Science. 2001. PMID: 11729323

4

PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.

Fang Y, Park IH, Wu AL, Du G, Huang P, Frohman MA, Walker SJ, Brown HA, Chen J. Fang Y, et al. Curr Biol. 2003 Dec 2;13(23):2037-44. doi: 10.1016/j.cub.2003.11.021. Curr Biol. 2003. PMID: 14653992 Free article.

5

Phospholipase D1 is an effector of Rheb in the mTOR pathway.

Sun Y, Fang Y, Yoon MS, Zhang C, Roccio M, Zwartkruis FJ, Armstrong M, Brown HA, Chen J. Sun Y, et al. Among authors: fang y. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8286-91. doi: 10.1073/pnas.0712268105. Epub 2008 Jun 11. Proc Natl Acad Sci U S A. 2008. PMID: 18550814 Free PMC article.

6

The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression.

Vilella-Bach M, Nuzzi P, Fang Y, Chen J. Vilella-Bach M, et al. Among authors: fang y. J Biol Chem. 1999 Feb 12;274(7):4266-72. doi: 10.1074/jbc.274.7.4266. J Biol Chem. 1999. PMID: 9933627 Free article.

7

XPLN is an endogenous inhibitor of mTORC2.

Khanna N, Fang Y, Yoon MS, Chen J. Khanna N, et al. Among authors: fang y. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):15979-84. doi: 10.1073/pnas.1310434110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043828 Free PMC article.

8

Duration of rapamycin treatment has differential effects on metabolism in mice.

Fang Y, Westbrook R, Hill C, Boparai RK, Arum O, Spong A, Wang F, Javors MA, Chen J, Sun LY, Bartke A. Fang Y, et al. Cell Metab. 2013 Mar 5;17(3):456-62. doi: 10.1016/j.cmet.2013.02.008. Cell Metab. 2013. PMID: 23473038 Free PMC article.

9

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

Simons M, Gault WJ, Gotthardt D, Rohatgi R, Klein TJ, Shao Y, Lee HJ, Wu AL, Fang Y, Satlin LM, Dow JT, Chen J, Zheng J, Boutros M, Mlodzik M. Simons M, et al. Among authors: fang y. Nat Cell Biol. 2009 Mar;11(3):286-94. doi: 10.1038/ncb1836. Epub 2009 Feb 22. Nat Cell Biol. 2009. PMID: 19234454 Free PMC article.

10

Effects of rapamycin on growth hormone receptor knockout mice.

Fang Y, Hill CM, Darcy J, Reyes-Ordoñez A, Arauz E, McFadden S, Zhang C, Osland J, Gao J, Zhang T, Frank SJ, Javors MA, Yuan R, Kopchick JJ, Sun LY, Chen J, Bartke A. Fang Y, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1495-E1503. doi: 10.1073/pnas.1717065115. Epub 2018 Jan 29. Proc Natl Acad Sci U S A. 2018. PMID: 29378959 Free PMC article.

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