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Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease.
Fleisher AS, Raman R, Siemers ER, Becerra L, Clark CM, Dean RA, Farlow MR, Galvin JE, Peskind ER, Quinn JF, Sherzai A, Sowell BB, Aisen PS, Thal LJ. Fleisher AS, et al. Arch Neurol. 2008 Aug;65(8):1031-8. doi: 10.1001/archneur.65.8.1031. Arch Neurol. 2008. PMID: 18695053 Free PMC article. Clinical Trial.
Alpha2 macroglobulin and the risk of Alzheimer's disease.
Dodel RC, Du Y, Bales KR, Gao F, Eastwood B, Glazier B, Zimmer R, Cordell B, Hake A, Evans R, Gallagher-Thompson D, Thompson LW, Tinklenberg JR, Pfefferbaum A, Sullivan EV, Yesavage J, Alstiel L, Gasser T, Farlow MR, Murphy GM Jr, Paul SM. Dodel RC, et al. Neurology. 2000 Jan 25;54(2):438-42. doi: 10.1212/wnl.54.2.438. Neurology. 2000. PMID: 10668709
Safety and tolerability of rivastigmine transdermal patch compared with rivastigmine capsules in patients switched from donepezil: data from three clinical trials.
Sadowsky CH, Farlow MR, Meng X, Olin JT. Sadowsky CH, et al. Int J Clin Pract. 2010 Jan;64(2):188-93. doi: 10.1111/j.1742-1241.2009.02253.x. Int J Clin Pract. 2010. PMID: 20089009
Chronic donepezil treatment is associated with slowed cognitive decline in Alzheimer's disease.
Doody RS, Dunn JK, Clark CM, Farlow M, Foster NL, Liao T, Gonzales N, Lai E, Massman P. Doody RS, et al. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):295-300. doi: 10.1159/000051272. Dement Geriatr Cogn Disord. 2001. PMID: 11351141 Clinical Trial.
A multicenter, randomized, placebo controlled, multiple-dose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients.
Grundman M, Capparelli E, Kim HT, Morris JC, Farlow M, Rubin EH, Heidebrink J, Hake A, Ho G, Schultz AN, Schafer K, Houston W, Thomas R, Thal LJ; Alzheimer's Disease Cooperative Study. Grundman M, et al. Life Sci. 2003 Jun 20;73(5):539-53. doi: 10.1016/s0024-3205(03)00320-5. Life Sci. 2003. PMID: 12770610 Clinical Trial.
IDEAL: a 6-month, double-blind, placebo-controlled study of the first skin patch for Alzheimer disease.
Winblad B, Grossberg G, Frölich L, Farlow M, Zechner S, Nagel J, Lane R. Winblad B, et al. Neurology. 2007 Jul 24;69(4 Suppl 1):S14-22. doi: 10.1212/01.wnl.0000281847.17519.e0. Neurology. 2007. PMID: 17646619 Clinical Trial.
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