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Chronic pain: the role of learning and brain plasticity.
Mansour AR, Farmer MA, Baliki MN, Apkarian AV. Mansour AR, et al. Among authors: farmer ma. Restor Neurol Neurosci. 2014;32(1):129-39. doi: 10.3233/RNN-139003. Restor Neurol Neurosci. 2014. PMID: 23603439 Free PMC article. Review.
The plastic changes that occur within this circuitry in relation to nociceptive inputs dictate the transition to chronic pain, rendering the pain less somatic and more affective in nature. ...We argue that the definition of chronic pain can be recast, within …
The plastic changes that occur within this circuitry in relation to nociceptive inputs dictate the transition to chronic pain, render …
A dynamic network perspective of chronic pain.
Farmer MA, Baliki MN, Apkarian AV. Farmer MA, et al. Neurosci Lett. 2012 Jun 29;520(2):197-203. doi: 10.1016/j.neulet.2012.05.001. Epub 2012 May 8. Neurosci Lett. 2012. PMID: 22579823 Free PMC article. Review.
We briefly summarize recent advances regarding brain functional representation of chronic pain, reorganization of resting state brain activity, and of brain anatomy with chronic pain. Based on these observations and recent theoretical advances regarding network arch …
We briefly summarize recent advances regarding brain functional representation of chronic pain, reorganization of resting state brain …
Predicting transition to chronic pain.
Apkarian AV, Baliki MN, Farmer MA. Apkarian AV, et al. Among authors: farmer ma. Curr Opin Neurol. 2013 Aug;26(4):360-7. doi: 10.1097/WCO.0b013e32836336ad. Curr Opin Neurol. 2013. PMID: 23823463 Free PMC article.
However, a small percentage continue to suffer, that is, transition to chronic pain. Chronic pain may persist for years and is accompanied by cognitive abnormalities, as well as diminished quality of life. ...SUMMARY: Properties of the brain's emotional learning cir …
However, a small percentage continue to suffer, that is, transition to chronic pain. Chronic pain may persist for years and is …
What is special about the vulvar vestibule?
Farmer MA. Farmer MA. Pain. 2015 Mar;156(3):359-360. doi: 10.1097/j.pain.0000000000000094. Pain. 2015. PMID: 25687538 Free PMC article.
The pathological underpinnings of localized provoked vulvodynia (LPV), the most prevalent cause of vulvar pain that is frequently comorbid with other variants of chronic pelvic pain, have evaded clinicians and scientists for decades. ...Foster and colleagues' findin …
The pathological underpinnings of localized provoked vulvodynia (LPV), the most prevalent cause of vulvar pain that is frequently com …
Predictors of genital pain in young women.
Farmer MA, Meston CM. Farmer MA, et al. Arch Sex Behav. 2007 Dec;36(6):831-43. doi: 10.1007/s10508-007-9199-7. Epub 2007 Aug 3. Arch Sex Behav. 2007. PMID: 17674182 Free PMC article.
We evaluated the sexual factors that impact the sexual function of women with any pain (including high and low pain groups) versus women with no history of pain. ...Women in the high pain group showed negative correlations between domains of sexual sat …
We evaluated the sexual factors that impact the sexual function of women with any pain (including high and low pain groups) ve …
Pain reduces sexual motivation in female but not male mice.
Farmer MA, Leja A, Foxen-Craft E, Chan L, MacIntyre LC, Niaki T, Chen M, Mapplebeck JC, Tabry V, Topham L, Sukosd M, Binik YM, Pfaus JG, Mogil JS. Farmer MA, et al. J Neurosci. 2014 Apr 23;34(17):5747-53. doi: 10.1523/JNEUROSCI.5337-13.2014. J Neurosci. 2014. PMID: 24760835 Free PMC article.
Chronic pain is often associated with sexual dysfunction, suggesting that pain can reduce libido. ...Pain-induced reductions in female sexual behavior were observed in the absence of sex differences in pain-related behavior, and could be rescued by the …
Chronic pain is often associated with sexual dysfunction, suggesting that pain can reduce libido. ...Pain-induced reduc …
Identifying brain nociceptive information transmission in patients with chronic somatic pain.
Davis DA, Ghantous ME, Farmer MA, Baria AT, Apkarian AV. Davis DA, et al. Among authors: farmer ma. Pain Rep. 2016 Oct;1(4):e575. doi: 10.1097/PR9.0000000000000575. Pain Rep. 2016. PMID: 28503674 Free PMC article.
INTRODUCTION: Recent advances regarding mechanisms of chronic pain emphasize the role of corticolimbic circuitry in predicting risk for chronic pain, independently from site of injury-related parameters. ...METHODS: Resting state functional MRI was used in a large g …
INTRODUCTION: Recent advances regarding mechanisms of chronic pain emphasize the role of corticolimbic circuitry in predicting risk f …
Brain functional and anatomical changes in chronic prostatitis/chronic pelvic pain syndrome.
Farmer MA, Chanda ML, Parks EL, Baliki MN, Apkarian AV, Schaeffer AJ. Farmer MA, et al. J Urol. 2011 Jul;186(1):117-24. doi: 10.1016/j.juro.2011.03.027. Epub 2011 May 14. J Urol. 2011. PMID: 21571326 Free PMC article.
Functional magnetic resonance imaging data were obtained from 14 patients with chronic prostatitis/chronic pelvic pain syndrome as they rated spontaneous pain inside the scanner. ...No group differences were found in regional gray matter volume, yet density of gray …
Functional magnetic resonance imaging data were obtained from 14 patients with chronic prostatitis/chronic pelvic pain syndrome as th …
Brain signature and functional impact of centralized pain: a multidisciplinary approach to the study of chronic pelvic pain (MAPP) network study.
Kutch JJ, Ichesco E, Hampson JP, Labus JS, Farmer MA, Martucci KT, Ness TJ, Deutsch G, Apkarian AV, Mackey SC, Klumpp DJ, Schaeffer AJ, Rodriguez LV, Kreder KJ, Buchwald D, Andriole GL, Lai HH, Mullins C, Kusek JW, Landis JR, Mayer EA, Clemens JQ, Clauw DJ, Harris RE; MAPP Research Network. Kutch JJ, et al. Among authors: farmer ma. Pain. 2017 Oct;158(10):1979-1991. doi: 10.1097/j.pain.0000000000001001. Pain. 2017. PMID: 28692006 Free PMC article.
This widespread pain is believed to be a marker of centralization, a central nervous system process that decouples pain perception from nociceptive input. ...These changes translated across disease diagnoses as identical outcomes were present in patients with fibrom …
This widespread pain is believed to be a marker of centralization, a central nervous system process that decouples pain percep …
Psychophysical properties of female genital sensation.
Farmer MA, Maykut CA, Huberman JS, Huang L, Khalifé S, Binik YM, Apkarian VA, Schweinhardt P. Farmer MA, et al. Pain. 2013 Nov;154(11):2277-2286. doi: 10.1016/j.pain.2013.05.028. Epub 2013 May 23. Pain. 2013. PMID: 23707679
Provoked vestibulodynia (PVD) is characterized by the presence of vulvar touch and pain hypersensitivity. Pain with vaginal distension, which motivates treatment seeking and perpetuates distress, is frequently reported with PVD. ...This investigation challenges the …
Provoked vestibulodynia (PVD) is characterized by the presence of vulvar touch and pain hypersensitivity. Pain with vaginal di …
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