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Mutations in ligands and receptors of the leptin-melanocortin pathway that lead to obesity.
Farooqi IS, O'Rahilly S. Farooqi IS, et al. Nat Clin Pract Endocrinol Metab. 2008 Oct;4(10):569-77. doi: 10.1038/ncpendmet0966. Epub 2008 Sep 9. Nat Clin Pract Endocrinol Metab. 2008. PMID: 18779842 Review.
Congenital leptin deficiency is associated with severe early-onset obesity in humans.
Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, O'Rahilly S. Montague CT, et al. Among authors: farooqi is. Nature. 1997 Jun 26;387(6636):903-8. doi: 10.1038/43185. Nature. 1997. PMID: 9202122
Effects of recombinant leptin therapy in a child with congenital leptin deficiency.
Farooqi IS, Jebb SA, Langmack G, Lawrence E, Cheetham CH, Prentice AM, Hughes IA, McCamish MA, O'Rahilly S. Farooqi IS, et al. N Engl J Med. 1999 Sep 16;341(12):879-84. doi: 10.1056/NEJM199909163411204. N Engl J Med. 1999. PMID: 10486419 No abstract available.
The role of melanocortin signalling in the control of body weight: evidence from human and murine genetic models.
Yeo GS, Farooqi IS, Challis BG, Jackson RS, O'Rahilly S. Yeo GS, et al. Among authors: farooqi is. QJM. 2000 Jan;93(1):7-14. doi: 10.1093/qjmed/93.1.7. QJM. 2000. PMID: 10623776 Review.
Genetics of body-weight regulation.
Barsh GS, Farooqi IS, O'Rahilly S. Barsh GS, et al. Among authors: farooqi is. Nature. 2000 Apr 6;404(6778):644-51. doi: 10.1038/35007519. Nature. 2000. PMID: 10766251 Review.
Recent advances in the genetics of severe childhood obesity.
Farooqi IS, O'Rahilly S. Farooqi IS, et al. Arch Dis Child. 2000 Jul;83(1):31-4. doi: 10.1136/adc.83.1.31. Arch Dis Child. 2000. PMID: 10868996 Free PMC article. Review.
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency.
Farooqi IS, Yeo GS, Keogh JM, Aminian S, Jebb SA, Butler G, Cheetham T, O'Rahilly S. Farooqi IS, et al. J Clin Invest. 2000 Jul;106(2):271-9. doi: 10.1172/JCI9397. J Clin Invest. 2000. PMID: 10903343 Free PMC article.
The CART gene and human obesity: mutational analysis and population genetics.
Challis BG, Yeo GS, Farooqi IS, Luan J, Aminian S, Halsall DJ, Keogh JM, Wareham NJ, O'Rahilly S. Challis BG, et al. Among authors: farooqi is. Diabetes. 2000 May;49(5):872-5. doi: 10.2337/diabetes.49.5.872. Diabetes. 2000. PMID: 10905499
Triple H syndrome: a novel autoimmune endocrinopathy characterized by dysfunction of the hippocampus, hair follicle, and hypothalamic-pituitary adrenal axis.
Farooqi IS, Jones MK, Evans M, O'Rahilly S, Hodges JR. Farooqi IS, et al. J Clin Endocrinol Metab. 2000 Aug;85(8):2644-8. doi: 10.1210/jcem.85.8.6753. J Clin Endocrinol Metab. 2000. PMID: 10946860 No abstract available.
Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population.
Halsall DJ, Luan J, Saker P, Huxtable S, Farooqi IS, Keogh J, Wareham NJ, O'Rahilly S. Halsall DJ, et al. Among authors: farooqi is. Int J Obes Relat Metab Disord. 2001 Apr;25(4):472-7. doi: 10.1038/sj.ijo.0801584. Int J Obes Relat Metab Disord. 2001. PMID: 11319649
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